行为基因组学研究的未来十年。
The next 10 years of behavioural genomic research.
作者信息
Plomin Robert
机构信息
King's College London Institute of Psychiatry Psychology and Neuroscience London UK.
出版信息
JCPP Adv. 2022 Nov 4;2(4):e12112. doi: 10.1002/jcv2.12112. eCollection 2022 Dec.
Abstract
BACKGROUND
The explosion caused by the fusion of quantitative genetics and molecular genetics will transform behavioural genetic research in child and adolescent psychology and psychiatry.
METHODS
Although the fallout has not yet settled, the goal of this paper is to predict the next 10 years of research in what could be called .
RESULTS
I focus on three research directions: the genetic architecture of psychopathology, causal modelling of gene-environment interplay, and the use of DNA as an early warning system.
CONCLUSION
Eventually, whole-genome sequencing will be available for all newborns, which means that behavioural genomics could potentially be applied ubiquitously in research and clinical practice.
摘要
背景
数量遗传学与分子遗传学的融合所引发的变革将改变儿童与青少年心理学及精神病学领域的行为遗传学研究。
方法
尽管影响尚未完全显现，但本文旨在预测未来10年在所谓的……方面的研究。
结果
我关注三个研究方向：精神病理学的遗传结构、基因-环境相互作用的因果建模以及将DNA用作早期预警系统。
结论
最终，全基因组测序将可用于所有新生儿，这意味着行为基因组学有可能在研究和临床实践中得到广泛应用。
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