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一名艾滋病毒患者的伯基特淋巴瘤非典型表现:以腹腔内巨大肿块压迫多个器官并累及心包周围组织,病例报告及文献综述

An Atypical Presentation of Burkitt Lymphoma Presenting As Large Intra-abdominal Masses Compressing Multiple Organs With Peri-Pericardial Involvement in an HIV Patient: A Case Report and Literature Review.

作者信息

Ugwendum Derek, Fernando Annmarie, Arrey Agbor Divine Besong, Ndemazie Nkafu Bechem, Forsah Sabastain F, Okorie Ikpechukwu J, Villanueva Kevin, Grigos Angela, Nfonoyim Jay

机构信息

Internal Medicine, Richmond University Medical Center, Staten Island, USA.

Radiology, Richmond University Medical Center, Staten Island, USA.

出版信息

Cureus. 2024 Feb 12;16(2):e54088. doi: 10.7759/cureus.54088. eCollection 2024 Feb.

Abstract

Many types of malignancies have been associated with immunodeficiency states, especially patients who are HIV positive. Burkitt lymphoma (BL) is one of those malignancies associated with HIV and it presents in three varieties. The endemic form is primarily seen in children, and it is associated with the Epstein-Barr virus (EBV). In this form, patients with Burkitt's present with a large jaw mass. The second variety is seen in older adults. These patients usually present with abdominal and pelvic masses. This subtype is more prominent in the United States. The third variety of BL is seen in patients who are HIV positive. In this case report, we present an atypical presentation of BL secondary to undiagnosed HIV/AIDS with a very large tumor burden causing compressive symptoms. This case will further guide healthcare professionals in diagnosing BL, which presents uniquely in high-risk populations. This report will also serve as a review of the diagnosis and treatment options of BL.

摘要

许多类型的恶性肿瘤都与免疫缺陷状态有关,尤其是艾滋病毒呈阳性的患者。伯基特淋巴瘤(BL)是与艾滋病毒相关的恶性肿瘤之一,它有三种类型。地方性伯基特淋巴瘤主要见于儿童,与爱泼斯坦-巴尔病毒(EBV)有关。在这种类型中,伯基特淋巴瘤患者表现为巨大的颌部肿块。第二种类型见于老年人。这些患者通常表现为腹部和盆腔肿块。这种亚型在美国更为突出。第三种类型的伯基特淋巴瘤见于艾滋病毒呈阳性的患者。在本病例报告中,我们呈现了一例因未确诊的艾滋病毒/艾滋病继发的非典型伯基特淋巴瘤,肿瘤负荷非常大,导致压迫症状。该病例将进一步指导医疗保健专业人员诊断伯基特淋巴瘤,它在高危人群中表现独特。本报告还将作为对伯基特淋巴瘤诊断和治疗选择的综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef55/10937252/88724630aaa8/cureus-0016-00000054088-i01.jpg

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