Department of Anaesthesiology and Intensive Therapy, University Medical Centre Ljubljana, Ljubljana, Slovenia; Institute of Anatomy, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia.
Department of Perinatology, Division of Obstetrics and Gynaecology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Biomol Biomed. 2024 Sep 6;24(5):1301-1309. doi: 10.17305/bb.2024.10186.
General anesthesia (GA) is typically recommended for category 1 emergency cesarean delivery (CD). For categories 2-4 emergencies, either regional or GA can be used. The factors influencing the choice of anesthetic technique in these categories remain poorly understood. We analyzed the association between the type of labor analgesia and subsequent anesthetic techniques employed for intrapartum categories 2 and 3 CD. In a prospective longitudinal cohort study, 300 women were consequently enrolled and categorized according to Lucas's classification of CD urgency. The techniques of anesthesia (GA, spinal, and epidural anesthesia [EA]) employed for CD were analyzed with respect to labor analgesia methods (remifentanil patient-controlled analgesia [remifentanil-PCA], EA, and nitrous oxide [N2O]). EA was the most frequent analgesic option (43.8%), followed by remifentanil-PCA (20.7%) and N2O (5.1%), while 30.4% of parturient women received no analgesia. All anesthetic methods showed a significant relationship with analgesic modalities (P < 0.001). Remifentanil-PCA was associated with a higher incidence of GA. Contraindication to EA was the primary factor related to the transition from remifentanil-PCA to GA. Most parturients who received EA were successfully converted to EA. Spinal anesthesia was the most common technique in women using N2O and those without labor analgesia. GA was associated with lower 5-min Apgar scores. The method of labor analgesia was associated with the anesthesia technique employed for categories 2 and 3 CD. This finding may guide patient counseling and intrapartum anesthetic planning. However, the analysis should be cautiously interpreted as the selection of anesthesia is a complex decision influenced by several clinical considerations.
全身麻醉(GA)通常被推荐用于 1 类紧急剖宫产(CD)。对于 2-4 类紧急情况,可以使用区域麻醉或 GA。这些类别中影响麻醉技术选择的因素仍了解甚少。我们分析了产程中 2 类和 3 类 CD 中与劳动镇痛类型相关的后续麻醉技术之间的关系。在一项前瞻性纵向队列研究中,连续纳入了 300 名妇女,并根据 Lucas 的 CD 紧急程度分类进行分类。分析了用于 CD 的麻醉技术(GA、脊髓和硬膜外麻醉[EA])与分娩镇痛方法(瑞芬太尼患者自控镇痛[瑞芬太尼-PCA]、EA 和一氧化二氮[N2O])之间的关系。EA 是最常见的镇痛选择(43.8%),其次是瑞芬太尼-PCA(20.7%)和 N2O(5.1%),而 30.4%的产妇未接受镇痛。所有麻醉方法与镇痛方式均呈显著相关(P < 0.001)。瑞芬太尼-PCA 与 GA 发生率升高相关。EA 的禁忌是从瑞芬太尼-PCA 转为 GA 的主要因素。接受 EA 的大多数产妇均成功转为 EA。使用 N2O 和无分娩镇痛的产妇最常采用脊髓麻醉。GA 与较低的 5 分钟 Apgar 评分相关。分娩镇痛方式与 2 类和 3 类 CD 所使用的麻醉技术相关。这一发现可能指导患者咨询和产程麻醉计划。但是,由于麻醉选择是受多种临床因素影响的复杂决策,因此应谨慎解释分析结果。