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[德国心理健康中心:促进预防、靶向干预和恢复力的创新性转化研究]

[The German Center for Mental Health : Innovative translational research to promote prevention, targeted intervention and resilience].

作者信息

Halil Melissa G, Baskow Irina, Zimdahl Malte F, Lipinski Silke, Hannig Rüdiger, Falkai Peter, Fallgatter Andreas J, Schneider Silvia, Walter Martin, Meyer-Lindenberg Andreas, Heinz Andreas

机构信息

Deutsches Zentrum für Psychische Gesundheit (DZPG), Standort Berlin-Potsdam, Berlin, Deutschland.

Klinik für Psychiatrie und Psychotherapie, Charité Universitätsmedizin Berlin, Charité Platz 1, 10117, Berlin, Deutschland.

出版信息

Nervenarzt. 2024 May;95(5):450-457. doi: 10.1007/s00115-024-01632-6. Epub 2024 Mar 15.

Abstract

BACKGROUND

Due to the high disease burden, the early onset and often long-term trajectories mental disorders are among the most widespread diseases with growing significance. The German Center for Mental Health (DZPG) was established to enhance research conditions and expedite the translation of clinically relevant findings into practice.

OBJECTIVE

The aim of the DZPG is to optimize mental healthcare in Germany, influence modifiable social causes and to develop best practice models of care for vulnerable groups. It seeks to promote mental health and resilience, combat the stigmatization associated with mental disorders, and contribute to the enhancement of treatment across all age groups.

MATERIAL AND METHODS

The DZPG employs a translational research program that accelerates the translation of basic research findings into clinical studies and general practice. University hospitals and outpatient departments, other university disciplines, and extramural research institutions are working together to establish a collaboratively coordinated infrastructure for accelerated translation and innovation.

RESEARCH PRIORITIES

The research areas encompass 1) the interaction of somatic and mental risk and resilience factors and disorders across the lifespan, 2) influencing relevant modifiable environmental factors and 3) based on this personalized prevention and intervention.

CONCLUSION

The DZPG aims to develop innovative preventive and therapeutic tools that enable an improvement in care for individuals with mental disorders. It involves a comprehensive integration of experts with experience at all levels of decision-making and employs trilogue and participatory approaches in all research projects.

摘要

背景

由于疾病负担沉重,精神障碍发病早且病程往往较长,是最为普遍且日益重要的疾病之一。德国心理健康中心(DZPG)的设立旨在改善研究条件,并加快将临床相关研究成果转化为实际应用。

目的

DZPG的目标是优化德国的精神卫生保健,影响可改变的社会成因,并为弱势群体开发最佳护理实践模式。它致力于促进心理健康和恢复力,消除与精神障碍相关的污名化现象,并推动各年龄段治疗水平的提高。

材料与方法

DZPG采用转化研究项目,加速将基础研究成果转化为临床研究和全科医疗。大学医院及门诊科室、其他大学学科以及校外研究机构共同努力,建立一个协同协调的基础设施,以加速转化和创新。

研究重点

研究领域包括1)全生命周期内躯体与精神风险、恢复力因素及障碍之间的相互作用,2)影响相关的可改变环境因素,以及3)基于此进行个性化预防和干预。

结论

DZPG旨在开发创新的预防和治疗工具,以改善对精神障碍患者的护理。它全面整合了各级决策层面具有经验的专家,并在所有研究项目中采用三方对话和参与式方法。

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