University of the Basque Country (UPV/EHU), Biscay, Spain.
Research Group: GIU21/042. Department of Stomatology, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), Barrio Sarriena s/n, Biscay, Leioa, 48940, Spain.
Clin Oral Investig. 2024 Mar 15;28(4):215. doi: 10.1007/s00784-024-05602-9.
To compare the clinical efficacy in terms of mean root coverage in RT2 recession treated with a coronally advanced flap combined with a xenogeneic collagen matrix versus a connective tissue graft.
A total of 20 patients were randomized to receive one of two treatments: coronally advanced flap + xenogeneic collagen matrix (test group) and coronally advanced flap + connective tissue graft (control group). Patient-related outcomes measures and professional aesthetic assessment by root esthetic score were performed. A descriptive and analytical statistical analysis of the variables was performed.
At 12 months, the mean root coverage was 56.48% in the test group and 69.72% in the control group (p = 0.048), with a 35% and 40% complete root coverage in the xenogeneic collagen matrix and connective tissue graft, respectively. Test group presented less pain (3.65 vs. 5.2 VAS units) (p = 0.015) and less surgical time (45 vs. 49.15 min) (p = 0.004) than control group.
The use of xenogeneic collagen matrix in RT2 recessions was effective for recession reduction to those obtained using autologous grafts; with the advantage that the duration of surgery and patient morbidity decreased. Therefore, xenogeneic collagen matrix in RT2 recessions could be an alternative to autologous grafts.
The use of xenogeneic collagen matrix decreases the surgery time and patient morbidity but connective tissue graft results in significantly better mean root coverage and complete root coverage. Xenogeneic collagen matrix can be used in the treatment of RT2 gingival recessions.
NCT03344315.
比较用冠向推进瓣联合异种胶原基质治疗 RT2 牙龈退缩与用结缔组织移植物治疗的临床疗效,以平均根覆盖率表示。
共 20 例患者随机分为两组:接受冠向推进瓣+异种胶原基质(试验组)和冠向推进瓣+结缔组织移植物(对照组)。进行了患者相关的结果测量和通过根美学评分进行的专业美学评估。对变量进行了描述性和分析性统计分析。
在 12 个月时,试验组的平均根覆盖率为 56.48%,对照组为 69.72%(p=0.048),异种胶原基质和结缔组织移植物的完全根覆盖率分别为 35%和 40%。试验组疼痛程度(3.65 比 5.2 VAS 单位)(p=0.015)和手术时间(45 比 49.15 分钟)(p=0.004)均低于对照组。
异种胶原基质在 RT2 退缩中的应用对减少退缩是有效的,与使用自体移植物相比;手术时间和患者发病率降低。因此,异种胶原基质在 RT2 退缩中可以替代自体移植物。
异种胶原基质的使用可减少手术时间和患者发病率,但结缔组织移植物可显著提高平均根覆盖率和完全根覆盖率。异种胶原基质可用于治疗 RT2 牙龈退缩。
NCT03344315。