Department of Quality Assurance, ISF College of Pharmacy, Moga, 142001, Punjab, India.
Department of Pharmaceutics, ISF College of Pharmacy, Moga, 142001, Punjab, India.
Infect Disord Drug Targets. 2024;24(8):e180324228044. doi: 10.2174/0118715265281694240223113930.
Every year witnesses an outbreak of some or the other zoonotic disease that causes the unparalled loss of human life. The year 2022 presented the outbreak of Crimean Congo haemorrhagic fever (CCHF), which brought unprecedented challenges to individuals as well as to the healthcare system all around the world, making it a serious health concern. Rising health concerns have highlighted the importance of managing and decreasing the further transmission of the CCHF virus. CCHF is one of tick-borne viral diseases, which spreads due to various reasons like changes in global warming, environmental influences, and other ecological factors. All these factors somehow impact the disease prevalence. This disease has a negative impact on both humans and livestock. The diverse climate and significant livestock population of India make it susceptible to the prevalence of CCHF. Therefore, it is the need of the hour to develop some strategies in order to tackle the challenges posed by CCHF. This article includes all the cases of CCHF that have occurred in India from the year 2011, along with the fatality rates associated with this disease. Also this study discusses the need to explore some specific drugs for the management and prevention of such diseases. In addition, the pathogenesis of the disease progression, along with some protective measures suggested by the government has been described for prevention of CCHF. Subsequently, this article attempted to draw attention towards the risk that may be posed by CCHF in the coming scenario, emphasizing the importance of taking proactive measures in anticipation of such risks.
每年都会爆发一些或其他的人畜共患病，给人类生命造成了无与伦比的损失。2022 年爆发了克里米亚刚果出血热（CCHF），给全世界的个人和医疗系统带来了前所未有的挑战，成为一个严重的健康问题。不断上升的健康问题凸显了管理和减少 CCHF 病毒进一步传播的重要性。CCHF 是一种蜱传病毒性疾病，由于全球变暖、环境影响和其他生态因素等各种原因而传播。所有这些因素都在某种程度上影响着疾病的流行。这种疾病对人类和牲畜都有负面影响。印度多样的气候和庞大的牲畜数量使其容易受到 CCHF 的流行影响。因此，现在需要制定一些策略来应对 CCHF 带来的挑战。本文包括了自 2011 年以来在印度发生的所有 CCHF 病例，以及与该疾病相关的死亡率。此外，本研究还讨论了需要探索一些特定药物来管理和预防此类疾病的必要性。此外，还描述了疾病进展的发病机制以及政府建议的一些预防措施。随后，本文试图提请人们注意 CCHF 在未来可能带来的风险，强调在预期这些风险时采取积极措施的重要性。
