Blackwell Thomas, Alvi Suffia, Curran Nicholas R, Germanwala Arpita
Otolaryngology Section, Department of Surgery, Jesse Brown VA Medical Center, Chicago, Illinois, USA.
Department of Otolaryngology, University of Illinois at Chicago College of Medicine, Chicago, Illinois, USA.
Laryngoscope. 2024 Aug;134(8):3555-3561. doi: 10.1002/lary.31397. Epub 2024 Mar 19.
There is a lack of a definitive study in the literature comparing early versus late tracheostomy and exploring the impact of tracheostomy timing on patient outcomes. This study may help guide treatment paradigms and contribute to a consensus for optimal tracheostomy timing.
A retrospective review was performed comparing early versus late timing of tracheostomy placement and their respective outcomes. The authors used data provided by VA Informatics and Computing Infrastructure (VINCI) to find patients who received a tracheostomy at any VA Medical Center in the United States. There were a total of 25,334 tracheostomies in the database which satisfied our criteria. These occurred between the years 1999 and 2022. Propensity score matching assessed 17,074 tracheostomies, 8537 in either group. The median age of patients in the matched groups was 66 years, and approximately 97.4% of patients were male. Early tracheostomy timing was defined as the placement of the tracheostomy within 10 days of intubation. Outcomes included post-tracheostomy intensive care unit (ICU) days, post-tracheostomy hospital days, successful ventilator weaning, and all-cause mortality.
Early tracheostomy was associated with significantly fewer ICU days and hospital days, and the early group experienced higher rates of successful ventilator weaning. Survival analysis of data within 5 years of tracheostomy showed that early tracheostomy was associated with significantly lower hazard for all-cause mortality.
Our results add to the body of evidence that an earlier transition to mechanical ventilation by tracheostomy confers benefits in patient morbidity and mortality as well as resource utilization.
3 Laryngoscope, 134:3555-3561, 2024.
文献中缺乏一项权威性研究来比较早期与晚期气管切开术,并探讨气管切开时机对患者预后的影响。本研究可能有助于指导治疗模式,并促成关于最佳气管切开时机的共识。
进行了一项回顾性研究,比较气管切开术的早期与晚期时机及其各自的预后。作者使用退伍军人事务部信息学和计算基础设施(VINCI)提供的数据,以找出在美国任何一家退伍军人事务部医疗中心接受气管切开术的患者。数据库中共有25334例气管切开术符合我们的标准。这些手术发生在1999年至2022年之间。倾向评分匹配评估了17074例气管切开术,每组8537例。匹配组患者的中位年龄为66岁,约97.4%的患者为男性。早期气管切开时机定义为在插管后10天内进行气管切开术。预后指标包括气管切开术后重症监护病房(ICU)住院天数、气管切开术后住院天数、成功脱机以及全因死亡率。
早期气管切开术与显著更少的ICU住院天数和住院天数相关,并且早期组成功脱机的比例更高。气管切开术后5年内的数据生存分析表明,早期气管切开术与全因死亡率的显著更低风险相关。
我们的结果进一步证明,通过气管切开术更早地过渡到机械通气在患者发病率、死亡率以及资源利用方面具有益处。
3 《喉镜》,134:3555 - 3561,2024年。