Department of acupuncture, Beijing Hospital of Traditional Chinese Medicine, Beijing 100010, China.
J Tradit Chin Med. 2024 Apr;44(2):388-395. doi: 10.19852/j.cnki.jtcm.20240203.004.
To explore the effect of electroacupuncture on skeletal muscle pain in Parkinson's disease (PD).
A single-center randomized controlled trial was conducted with sixty patients with Parkinson's disease with skeletal muscle pain were randomly divided into electroacupuncture group and sham acupuncture control group with 30 patients each. The electric acupuncture group was treated with electric acupuncture, while the control group was treated with Park needle pseudoacupuncture. Both groups were treated 5 times a week for a total of 4 weeks, and both groups completed 20 treatments. King's Parkinson's Pain Scale (KPPS) and visual analog scale (VAS) were used before and after treatment to evaluate the pain degree of patients. Real-time shear wave elastography (SWE) and modified Ashworth score (MAS) were used to evaluate the changes of muscle tone. Parkinson's comprehensive Score Scale (MDS-UPDRS, including UPDRSⅡ and UPDRS Ⅲ) was used to evaluate exercise ability. Hamilton Depression Scale (HAMD) score was used to evaluate the emotional changes of patients. Spearman correlation analysis was used to explore the correlation between pain degree and muscle tone, exercise ability and emotion.
During the study, one case fell off in the control group, and 30 cases were eventually included in the analysis and treatment group and 29 cases in the control group. After treatment, Young's modulus of biceps and quadriceps and shear wave velocity of biceps were decreased in electroacupuncture group compared with before treatment, while KPPS score, VAS score, UPDRSⅡ, UPDRS Ⅲ and modified Ashworth score were decreased, with statistical significance ( 0.05). There was no statistical significance in control group ( 0.05). After treatment, KPPS score, VAS score, UPDRSⅡ and UPDRS Ⅲ, MAS, HAMD score, Young's modulus of biceps and shear wave velocity in electroacupuncture group were significantly lower than those in control group ( 0.05). Spearman correlation analysis showed that KPPS score was positively correlated with UPDRS Ⅲ ( = 0.414, 0.05). KPPS score was positively correlated with HAMD score ( = 0.576, 0.01).
Electroacupuncture therapy can effectively improve skeletal muscle pain in patients with Parkinson's disease, reduce the muscle hardness of patients, improve patients' daily life ability, and improve patients' emotional disorders. The degree of skeletal muscle pain in PD patients is correlated with motor ability and emotional disorders, but there is no significant correlation between the degree of skeletal muscle pain and the muscle tone of PD patients.
探讨电针对帕金森病（PD）患者骨骼肌疼痛的影响。
采用单中心随机对照试验，将 60 例帕金森病伴骨骼肌疼痛患者随机分为电针组和假针刺对照组，每组 30 例。电针组采用电针治疗，对照组采用 Park 针伪针刺治疗。两组均每周治疗 5 次，共 4 周，共治疗 20 次。治疗前后采用帕金森病疼痛量表（KPPS）和视觉模拟评分（VAS）评估患者疼痛程度。采用实时剪切波弹性成像（SWE）和改良 Ashworth 评分（MAS）评估肌肉紧张度的变化。采用帕金森综合评分量表（MDS-UPDRS，包括 UPDRSⅡ和 UPDRS Ⅲ）评估运动能力。采用汉密尔顿抑郁量表（HAMD）评分评估患者情绪变化。采用 Spearman 相关分析探讨疼痛程度与肌肉紧张度、运动能力和情绪的相关性。
研究过程中，对照组脱落 1 例，最终分析和治疗组纳入 30 例，对照组纳入 29 例。电针组治疗后肱二头肌和股四头肌杨氏模量及肱二头肌剪切波速度较治疗前降低，KPPS 评分、VAS 评分、UPDRSⅡ、UPDRS Ⅲ和改良 Ashworth 评分降低，差异有统计学意义（ 0.05）。对照组差异无统计学意义（ 0.05）。治疗后，电针组 KPPS 评分、VAS 评分、UPDRSⅡ、UPDRS Ⅲ、MAS、HAMD 评分、肱二头肌杨氏模量及剪切波速度均明显低于对照组，差异有统计学意义（ 0.05）。Spearman 相关分析显示，KPPS 评分与 UPDRS Ⅲ呈正相关（ = 0.414， 0.05）。KPPS 评分与 HAMD 评分呈正相关（ = 0.576， 0.01）。
电针疗法可有效改善帕金森病患者骨骼肌疼痛，降低患者肌肉硬度，提高患者日常生活能力，改善患者情绪障碍。PD 患者骨骼肌疼痛程度与运动能力和情绪障碍相关，但与 PD 患者肌肉紧张度无明显相关性。
