Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL, USA; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA.
Department of Pathology, Health Sciences Center, University of New Mexico, Albuquerque, NM, USA.
Drug Discov Today. 2024 May;29(5):103953. doi: 10.1016/j.drudis.2024.103953. Epub 2024 Mar 18.
The Illuminating the Druggable Genome (IDG) consortium generated reagents, biological model systems, data, informatic databases, and computational tools. The Resource Dissemination and Outreach Center (RDOC) played a central administrative role, organized internal meetings, fostered collaboration, and coordinated consortium-wide efforts. The RDOC developed and deployed a Resource Management System (RMS) to enable efficient workflows for collecting, accessing, validating, registering, and publishing resource metadata. IDG policies for repositories and standardized representations of resources were established, adopting the FAIR (findable, accessible, interoperable, reusable) principles. The RDOC also developed metrics of IDG impact. Outreach initiatives included digital content, the Protein Illumination Timeline (representing milestones in generating data and reagents), the Target Watch publication series, the e-IDG Symposium series, and leveraging social media platforms.
照亮可用药基因组（IDG）联盟生成了试剂、生物模型系统、数据、信息数据库和计算工具。资源传播和拓展中心（RDOC）发挥了核心管理作用，组织内部会议，促进合作，并协调全联盟的努力。RDOC 开发并部署了资源管理系统（RMS），以实现资源元数据的收集、访问、验证、注册和发布的高效工作流程。IDG 为存储库和资源的标准化表示方式制定了政策，采用了 FAIR（可发现、可访问、可互操作、可重用）原则。RDOC 还制定了 IDG 影响的指标。拓展计划包括数字内容、蛋白质照亮时间表（代表生成数据和试剂的里程碑）、目标观察出版物系列、电子 IDG 研讨会系列，以及利用社交媒体平台。
