Research Center for Bioscience and Nanoscience (CeBN), Research Institute for Marine Resources Utilization (MRU), Japan Agency for Marine-Earth Science and Technology (JAMSTEC).
Institute for Chemical Research, Kyoto University.
Microbes Environ. 2024;39(1). doi: 10.1264/jsme2.ME23061.
With the explosion of available genomic information, comparative genomics has become a central approach to understanding microbial ecology and evolution. We developed DiGAlign (https://www.genome.jp/digalign/), a web server that provides versatile functionality for comparative genomics with an intuitive interface. It allows the user to perform the highly customizable visualization of a synteny map by simply uploading nucleotide sequences of interest, ranging from a specific region to the whole genome landscape of microorganisms and viruses. DiGAlign will serve a wide range of biological researchers, particularly experimental biologists, with multifaceted features that allow the rapid characterization of genomic sequences of interest and the generation of a publication-ready figure.
随着基因组信息的爆炸式增长，比较基因组学已成为理解微生物生态和进化的核心方法。我们开发了 DiGAlign（https://www.genome.jp/digalign/），这是一个提供多功能比较基因组学功能的网络服务器，具有直观的界面。它允许用户通过简单地上传感兴趣的核苷酸序列，从特定区域到微生物和病毒的整个基因组景观，执行高度可定制的同线性图谱可视化。DiGAlign 将为广泛的生物研究人员，特别是实验生物学家，提供多方面的功能，允许快速描述感兴趣的基因组序列，并生成可发表的图形。
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