Wang Dan, Wang Qi, Wang Yunhe, Li Ting, Tian Mi
Department of Endocrinology, Metabolism and Gastroenterology, Third Affiliated Clinical Hospital to Changchun University of Chinese Medicine, Changchun 130117, Jilin, China.
College of Acupuncture and Massage, Changchun University of Chinese Medicine, Changchun 130117, Jilin Province, China.
Heliyon. 2024 Mar 8;10(6):e27524. doi: 10.1016/j.heliyon.2024.e27524. eCollection 2024 Mar 30.
Ulcerative colitis (UC) is a gastrointestinal disease with an unknown etiology that severely affects patients' quality of life. Acupuncture and moxibustion therapies are effective in the treatment of UC, but existing systematic reviews (SRs) and meta-analyses (MAs) on this subject have variable methodological and outcome quality. Therefore, this study aimed to summarize and evaluate the evidence of existing SRs and MAs to provide more reliable evidence for clinical practice. Data were extracted from seven databases through systematic search and evaluated in terms of the methodological quality, reporting quality, risk of bias, and quality of evidence using the AMSTAR-2, PRISMA, ROBIS, and GRADE systems, respectively. Ten studies were finally included, and all of them showed many problems with the overall design and quality of outcomes. Because of the lack of high-quality evidence to support the findings from the existing studies, we should take this conclusion with caution and strictly implement the registration, design, and implementation of trials based on evidence to provide high-quality results in future studies.
溃疡性结肠炎(UC)是一种病因不明的胃肠道疾病,严重影响患者的生活质量。针灸疗法对UC的治疗有效,但关于该主题的现有系统评价(SRs)和荟萃分析(MAs)在方法学和结果质量方面存在差异。因此,本研究旨在总结和评估现有SRs和MAs的证据,为临床实践提供更可靠的证据。通过系统检索从七个数据库中提取数据,并分别使用AMSTAR-2、PRISMA、ROBIS和GRADE系统从方法学质量、报告质量、偏倚风险和证据质量方面进行评估。最终纳入了十项研究,所有这些研究在总体设计和结果质量方面都存在许多问题。由于缺乏高质量证据支持现有研究的结果,我们应谨慎对待这一结论,并严格按照证据实施试验的注册、设计和实施,以便在未来研究中提供高质量的结果。