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具有错配修复蛋白 proficient 表型的乙状结肠锯齿状腺癌:结直肠癌一种新亚型的组织病理学识别

Serrated adenocarcinoma of sigmoid colon with mismatch repair protein-proficient phenotype: Histopathological recognition of a new subtype of colorectal adenocarcinoma.

作者信息

Karki Diksha, Ngakhusi Sajan

机构信息

Department of Pathology Bhaktapur Cancer Hospital Bhaktapur Bagmati Nepal.

出版信息

Clin Case Rep. 2024 Mar 19;12(3):e8669. doi: 10.1002/ccr3.8669. eCollection 2024 Mar.

Abstract

Serrated adenocarcinoma is a distinct subtype of colorectal carcinoma characterized by unique histological and molecular features. Here we present a case study of a 58-year-old female patient who presented with generalized weakness, abdominal discomfort, and per-rectal bleeding. This case report highlights the importance of understanding the histopathological features of serrated adenocarcinoma for accurate diagnosis which has impact on further management.

摘要

锯齿状腺癌是结直肠癌的一种独特亚型,具有独特的组织学和分子特征。在此,我们报告一例58岁女性患者的病例研究,该患者表现为全身乏力、腹部不适和直肠出血。本病例报告强调了了解锯齿状腺癌的组织病理学特征对于准确诊断的重要性,这对进一步的治疗有影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42e3/10950788/8c52cbb16864/CCR3-12-e8669-g005.jpg

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