Department of Hematology/Oncology, Henry Ford Health System, Detroit, MI 48202, USA.
Nutrients. 2019 Jan 14;11(1):164. doi: 10.3390/nu11010164.
Colorectal Cancer is the third most common cancer diagnosed in the US. While the incidence and the mortality rate of colorectal cancer has decreased due to effective cancer screening measures, there has been an increase in number of young patients diagnosed in colon cancer due to unclear reasons at this point of time. While environmental and genetic factors play a major role in the pathogenesis of colon cancer, extensive research has suggested that nutrition may play both a causal and protective role in the development of colon cancer. In this review article, we aim to provide a review of factors that play a major role in development of colorectal cancer.
在美国，结直肠癌是第三大常见的癌症。尽管由于有效的癌症筛查措施，结直肠癌的发病率和死亡率有所下降，但由于目前尚不清楚的原因，年轻患者的结肠癌诊断数量有所增加。虽然环境和遗传因素在结肠癌的发病机制中起主要作用，但大量研究表明，营养可能在结肠癌的发展中起因果和保护作用。在这篇综述文章中，我们旨在综述在结直肠癌发展中起主要作用的因素。
