University of Health Sciences, Adana City Training and Research Hospital, Department of Gastroenterology - Adana, Turkey.
Muğla Training and Research Hospital, Department of Gastroenterology - Muğla, Turkey.
Rev Assoc Med Bras (1992). 2024 Mar 15;70(1):e20230810. doi: 10.1590/1806-9282.20230810. eCollection 2024.
Acute pancreatitis is a rare disease in pregnant patients. Although it may have serious maternal and fetal consequences, morbidity and mortality rates have decreased recently due to appropriate and rapid treatment with earlier diagnosis. The aim of this study was to evaluate pregnant patients diagnosed with acute pancreatitis.
The study included pregnant patients diagnosed with acute pancreatitis who were admitted to Adana City Training and Research Hospital in Adana, Turkey, between January 2014 and January 2022. Patients' files were screened. Patients' demographics, acute pancreatitis etiology, severity, complications, and applied treatment, as well as maternal and fetal outcomes were evaluated.
The study included 65 pregnant patients with acute pancreatitis. The mean age was 26.6±5 (19-41) years. Acute pancreatitis was observed in the third trimester. The most common cause of acute pancreatitis was gallstones, and its severity was often mild. Only two patients required endoscopic retrograde cholangiopancreatography, and the remaining patients were treated medically. Maternal and infant death developed in a patient with necrotizing acute pancreatitis secondary to hyperlipidemia.
The most common etiology of acute pancreatitis in pregnancy was gallstones. Acute pancreatitis occurred in the third trimester. Most of the patients had mild acute pancreatitis. Maternal and fetal complications were rare. We think that the reasons for the low mortality rate were mild disease severity and biliary etiology, and most patients were in the third trimester, as well as early diagnosis and no delay in the intervention.
急性胰腺炎在孕妇中较为罕见。尽管它可能对母婴有严重的影响,但由于早期诊断和及时治疗,其发病率和死亡率近年来已有所下降。本研究旨在评估诊断为急性胰腺炎的孕妇患者。
该研究纳入了 2014 年 1 月至 2022 年 1 月期间在土耳其阿达纳市培训与研究医院就诊的诊断为急性胰腺炎的孕妇患者。筛选了患者的病历,评估了患者的人口统计学特征、急性胰腺炎的病因、严重程度、并发症、应用的治疗方法以及母婴结局。
该研究共纳入了 65 例诊断为急性胰腺炎的孕妇患者,平均年龄为 26.6±5(19-41)岁,急性胰腺炎发生于妊娠晚期。急性胰腺炎最常见的病因是胆石症,严重程度通常较轻。仅 2 例患者需要接受内镜逆行胰胆管造影术,其余患者接受了内科治疗。1 例因高脂血症导致坏死性急性胰腺炎的患者死亡。
妊娠期间急性胰腺炎最常见的病因是胆石症,发生于妊娠晚期,大多数患者为轻度急性胰腺炎,母婴并发症罕见。我们认为,死亡率低的原因是疾病严重程度较轻且病因是胆源性,以及大多数患者处于妊娠晚期,此外还得益于早期诊断和及时干预。