College of Pharmacy, Jiamusi University, Jiamusi 154007, China.
School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710049, China.
J Asian Nat Prod Res. 2024 Jul;26(7):795-802. doi: 10.1080/10286020.2024.2323202. Epub 2024 Mar 21.
Two new sesquiterpenoid glycosides, 8 ()-eudesmane-1,3,11 (13)-triene-2-one -12---D-glucopyranoside () and dmetelisproside B (), together with ten known compounds (-) were isolated from calyces of L. var. (Mast.) Makino (PAF). Their structures were unambiguously elucidated through HR-ESI-MS, UV, IR, and NMR spectral data. Compounds , , and exhibited DPPH scavenging ability with IC values of 33.69 ± 6.65, 6.29 ± 0.06, and 25.66 ± 3.06 M, respectively. Additionally, and demonstrated weak α-glucosidase inhibition activity with IC values of 250.9 ± 6.60 and 347.6 ± 2.48 M, respectively.
从 L. var. (Mast.) Makino (PAF) 的花萼中分离得到了两种新的倍半萜糖苷，8 ()-桉叶烷-1,3,11 (13)-三烯-2-酮-12---D-吡喃葡萄糖苷 () 和 dmetelisproside B ()，以及十种已知化合物 (-)。通过高分辨电喷雾质谱（HR-ESI-MS）、紫外（UV）、红外（IR）和核磁共振（NMR）光谱数据，明确鉴定了它们的结构。化合物 、 、和 具有 DPPH 清除能力，其 IC 值分别为 33.69 ± 6.65、6.29 ± 0.06 和 25.66 ± 3.06 M。此外， 和 对 α-葡萄糖苷酶表现出较弱的抑制活性，其 IC 值分别为 250.9 ± 6.60 和 347.6 ± 2.48 M。
