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对遗传性球形红细胞增多症的 6 岁女童,行最小化内镜下括约肌切开术,随后行乳头球囊扩张术,以解除胆总管结石。

Minimal endoscopic sphincterotomy followed by papillary balloon dilation to relieve choledocholithiasis in a 6-year-old girl with hereditary spherocytosis.

机构信息

Department of Gastroenterology, Tokyo Metropolitan Children's Medical Center, 2-8-29, Musashidai, Fuchu-shi, Tokyo, 183-8561, Japan.

Department of Gastroenterology, Tokyo Metropolitan Tama Medical Center, 2-8-29, Musashidai, Fuchu-shi, Tokyo, 183-8524, Japan.

出版信息

Clin J Gastroenterol. 2024 Aug;17(4):782-787. doi: 10.1007/s12328-024-01960-9. Epub 2024 Mar 22.

Abstract

A 6-year-old girl previously diagnosed with hereditary spherocytosis was admitted to our hospital with gallstones and cholangitis. Endoscopic retrograde cholangiopancreatography (ERCP) was performed, and fluoroscopy revealed a dilated common bile duct (CBD) without evident stones, possibly due to spontaneous excretion through the papilla of Vater. A 7-French plastic stent was inserted into the CBD. After the procedure, a marked increase in pancreatic enzyme levels was observed, and she was diagnosed with post-ERCP pancreatitis (PEP). Stent placement could have been a cause of pancreatitis; therefore, we removed the stent. Subsequently, recovery from pancreatitis was confirmed, although she suddenly complained of abdominal pain and was diagnosed with choledocholithiasis recurrence. ERCP was repeated, and fluoroscopy revealed a dilated CBD with a stone. A minimal endoscopic sphincterotomy (EST) was performed to reduce the risk of PEP, and a biliary dilation balloon placed across the papilla was gradually inflated until the waist of the balloon disappeared. Stones were extracted using a retrieval balloon catheter. The abdominal pain resolved immediately, and the patient recovered without developing PEP. To our knowledge, this is the first case report of a pediatric patient treated with minimal EST followed by papillary balloon dilation for choledocholithiasis.

摘要

一名 6 岁女孩曾被诊断为遗传性球形红细胞增多症,因胆结石和胆管炎入院。进行了内镜逆行胰胆管造影术(ERCP),透视显示胆总管(CBD)扩张但未见明显结石,可能是通过 Vater 乳头自发排出。将一根 7Fr 的塑料支架置入 CBD。术后观察到胰腺酶水平显著升高,诊断为 ERCP 后胰腺炎(PEP)。支架置入可能是胰腺炎的原因,因此我们移除了支架。随后,胰腺炎得到了确认,尽管她突然出现腹痛并被诊断为胆石症复发。再次进行 ERCP,透视显示 CBD 扩张且有结石。为了降低 PEP 的风险,进行了最小化的内镜下括约肌切开术(EST),将一个胆道扩张球囊放在乳头处逐渐充气,直到球囊腰部消失。使用取石球囊导管取出结石。腹痛立即缓解,患者未发生 PEP 而康复。据我们所知,这是首例采用最小化 EST 联合乳头球囊扩张治疗小儿胆总管结石的病例报告。

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