Zhao Yanrong, Yuan Xiaoxue, Lin Tianxiang, Yang Qing, Jiang Xuewen, Yang Song, Qiu Yinwei
Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, 310051, China.
Beijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, 100015, China.
Diabetol Metab Syndr. 2024 Mar 23;16(1):74. doi: 10.1186/s13098-024-01312-0.
Alcohol consumption and metabolic syndrome(MetS), both prevalent in the general population, frequently co-occur. They are recognized as significant contributors to liver dysfunction, yet their combined effect is often challenging to delineate. This study delves into the compounding influence of alcohol consumption and metabolic disorder on liver dysfunction within an elderly demographic in Zhejiang Province, China. Our findings spotlight a heightened risk of liver dysfunction among females, younger individuals, rural dwellers, those with minimal educational attainment, single individuals, and those diagnosed with MetS. We also discerned a positive correlation correlation between the number of MetS components and the propensity for liver dysfunction. Furthermore, the risk of liver dysfunction escalated in tandem with the frequency of alcohol consumption. Interestingly, a prolonged abstinence period (≥ 5 years) seemed to mitigate this risk. Our research underscores the significance of refraining from excessive alcohol consumption, embracing a healthy lifestyle, and managing MetS components-especially triglyceride levels-for effective prevention of liver dysfunction.
饮酒与代谢综合征（MetS）在普通人群中都很常见，且经常同时出现。它们被认为是导致肝功能障碍的重要因素，但其综合影响往往难以界定。本研究深入探讨了在中国浙江省老年人群中，饮酒和代谢紊乱对肝功能障碍的复合影响。我们的研究结果表明，女性、年轻人、农村居民、受教育程度低的人、单身人士以及被诊断患有MetS的人肝功能障碍风险更高。我们还发现MetS各组成部分的数量与肝功能障碍倾向之间存在正相关。此外，肝功能障碍的风险随着饮酒频率的增加而上升。有趣的是，长期戒酒（≥5年）似乎可以降低这种风险。我们的研究强调了避免过度饮酒、保持健康生活方式以及控制MetS各组成部分——尤其是甘油三酯水平——对于有效预防肝功能障碍的重要性。
