Ma Fei, Kang Min, Liao Ye Hui, Lee Guang Zhou, Tang Qiang, Tang Chao, Ding Yin Huan, Zhong De Jun
Department of Spine Surgery.
Department of Gastroenterology.
Medicine (Baltimore). 2018 Dec;97(49):e13541. doi: 10.1097/MD.0000000000013541.
Nocardial spinal epidural abscess is rare. The diagnosis is often difficult to make and, if delayed, poses a high risk of long-term disability. Nocardial spinal epidural abscess with severe lumbar disc herniation has not previously been reported.
A 50-year-old man presented with progressive lumbago and leg pain for 6 weeks after receiving acupuncture therapy, and then the patient suddenly occurred urine retention after walking.
Clinical examination revealed sign of cauda equina syndrome. Magnetic resonance imaging (MRI) revealed a Lumbar(L)4 to L5 disc herniation, L3 to Sacrum(S)1 epidural abscess, and L2 to S1 paravertebral abscess. The causative organism was Nocardia farcinica.
An urgent paravertebral abscess debridement and right L4 to L5 laminectomy were performed. Simultaneously, the disc tissue protruding into the spinal canal was removed, as well as irrigation and drainage. And antimicrobial treatment was continued for 12 months.
Fortunately, the patient was able to walk with a cane and urinate autonomously without a catheter, although this remained difficult 7 days after surgery. After 1 year of treatment, the patient has recovered completely and returned to work.
Nocardial spinal epidural abscess with severe lumbar disc herniation is extremely rare. Pain from spinal degenerative diseases often masks the early symptoms of spinal infection. It's worth noting that invasive treatment of spine is a way of causing spinal nocardial infection.
诺卡菌性脊柱硬膜外脓肿较为罕见。诊断往往困难,若延误诊断则会带来长期残疾的高风险。此前尚未有诺卡菌性脊柱硬膜外脓肿合并严重腰椎间盘突出症的报道。
一名50岁男性在接受针灸治疗6周后出现进行性腰痛和腿痛,之后行走时突然出现尿潴留。
临床检查发现马尾综合征体征。磁共振成像(MRI)显示腰4至腰5椎间盘突出、腰3至骶1硬膜外脓肿以及腰2至骶1椎旁脓肿。致病微生物为豚鼠耳炎诺卡菌。
紧急进行椎旁脓肿清创术及右侧腰4至腰5椎板切除术。同时,切除突入椎管的椎间盘组织,并进行冲洗和引流。抗菌治疗持续12个月。
幸运的是,患者术后7天虽仍行走困难,但已能拄拐行走且自主排尿无需导尿管。经过1年治疗,患者已完全康复并重返工作岗位。
诺卡菌性脊柱硬膜外脓肿合并严重腰椎间盘突出症极为罕见。脊柱退行性疾病引起的疼痛常掩盖脊柱感染的早期症状。值得注意的是,脊柱的侵入性治疗是导致脊柱诺卡菌感染的一种途径。