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比较预测产科危急重症的预警系统的疗效。

Comparison of the efficacy for early warning systems in predicting obstetric critical illness.

机构信息

Department of Obstetrics and Gynecology Intensive Care Unit, West China Women's and Children's Hospital, Sichuan University, China.

Department of Obstetrics and Gynecology Intensive Care Unit, West China Women's and Children's Hospital, Sichuan University, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, China.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2024 May;296:327-332. doi: 10.1016/j.ejogrb.2024.03.025. Epub 2024 Mar 19.

Abstract

OBJECTIVE

To validate the accuracy of four early warning scores for early identification of women at risk.

METHODS

This was a retrospective study of pregnant women admitted in obstetrics Critical Care Unit (ICU). Capacity of the Modified Obstetric Early Warning Score (MOEWS), ICNARC Obstetric Early Warning Score (OEWS), Maternal Early Obstetric Warning System (MEOWS chart), and Maternal Early Warning Trigger (MEWT) were compared in predicting severe maternal morbidity. Area under receiver operator characteristic (AUROC) curve was used to evaluate the predictive performance of scoring system.

RESULTS

A total of 352 pregnant women were enrolled and 290 were identified with severe maternal morbidity. MOEWS was more sensitive than MEOWS chart, ICNARC OEWS and MEWT (96.9 % vs. 83.4 %, 66.6 % and 44.8 %). MEWT had the highest specificity (98.4 %), followed by MOEWS (83.9 %), ICNARC OEWS (75.8 %) and MEOWS chart (48.4 %). AUROC of MOEWS, ICNARC OEWS, MEOWS chart, and MEWT for prediction of maternal mortality were 0.91 (95 % CI: 0.874-0.945), 0.765(95 % CI: 0.71-0.82), 0.657(95 % CI: 0.577-0.738), and 0.716 (95 % CI, 0.659-0.773) respectively. MOEWS had the highest AUCs in the discrimination of serious complications in hypertensive disorders, cardiovascular disease, obstetric hemorrhage and infection. For individual vital signs, maximum diastolic blood pressure (DBP), maximum systolic blood pressure (SBP), maximum respiratory rate (RR) and peripheral oxygen saturation (SPO2) demonstrated greater predictive ability.

CONCLUSION

MOEWS is more accurate than ICNARC OEWS, MEOWS chart, and MEWT in predicting the deterioration of women. The prediction ability of DBP, SBP, RR and SPO2 are more reliable.

摘要

目的

验证四种早期预警评分对识别高危女性的准确性。

方法

这是一项回顾性研究,纳入了在产科重症监护病房(ICU)就诊的孕妇。比较改良产科早期预警评分(MOEWS)、国际危重医学协会产科早期预警评分(ICNARC OEWS)、产妇早期产科预警系统(MEOWS 图表)和产妇早期预警触发(MEWT)在预测严重产妇发病率方面的能力。接受者操作特征(ROC)曲线下面积(AUROC)用于评估评分系统的预测性能。

结果

共纳入 352 例孕妇,其中 290 例发生严重产妇发病率。MOEWS 比 MEOWS 图表、ICNARC OEWS 和 MEWT 更敏感(96.9% vs. 83.4%、66.6%和 44.8%)。MEWT 的特异性最高(98.4%),其次是 MOEWS(83.9%)、ICNARC OEWS(75.8%)和 MEOWS 图表(48.4%)。MOEWS、ICNARC OEWS、MEOWS 图表和 MEWT 预测产妇死亡率的 AUROC 分别为 0.91(95%CI:0.874-0.945)、0.765(95%CI:0.71-0.82)、0.657(95%CI:0.577-0.738)和 0.716(95%CI,0.659-0.773)。MOEWS 在区分高血压疾病、心血管疾病、产科出血和感染等严重并发症方面具有最高的 AUC。对于个体生命体征,最大舒张压(DBP)、最大收缩压(SBP)、最大呼吸率(RR)和外周血氧饱和度(SPO2)具有更高的预测能力。

结论

MOEWS 在预测女性病情恶化方面比 ICNARC OEWS、MEOWS 图表和 MEWT 更准确。DBP、SBP、RR 和 SPO2 的预测能力更可靠。

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