• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

使用孕产妇早期预警触发工具可降低孕产妇发病率。

Use of Maternal Early Warning Trigger tool reduces maternal morbidity.

作者信息

Shields Laurence E, Wiesner Suzanne, Klein Catherine, Pelletreau Barbara, Hedriana Herman L

机构信息

Maternal Fetal Medicine, Marian Regional Medical Center, Santa Maria, CA; Department of Patient Safety, Dignity Health, San Francisco, CA.

Department of Patient Safety, Dignity Health, San Francisco, CA.

出版信息

Am J Obstet Gynecol. 2016 Apr;214(4):527.e1-527.e6. doi: 10.1016/j.ajog.2016.01.154. Epub 2016 Feb 28.

DOI:10.1016/j.ajog.2016.01.154
PMID:26924745
Abstract

BACKGROUND

Maternal mortality in the United States has increased unabated for the past 20 years. Maternal morbidity is also affecting an increasingly large number of women in the United States. A number of national and state organizations have recommend the use of maternal early warning tools as a method to combat this problem. There are limited data suggesting that the use of these types of clinical assessment tools can reduce maternal morbidity.

OBJECTIVE

We sought to determine if maternal morbidity could be reduced with the implementation of a clinical pathway-specific Maternal Early Warning Trigger (MEWT) tool.

STUDY DESIGN

The tool was developed internally and prospectively implemented as a pilot project in 6 of 29 hospitals within a large hospital system. The primary goal was early assessment and treatment of patients suspected of clinical deterioration. The tool addressed the 4 most common areas of maternal morbidity: sepsis, cardiopulmonary dysfunction, preeclampsia-hypertension, and hemorrhage. To be considered positive, triggers needed to be sustained for >20 minutes and were defined as severe (single abnormal value): maternal heart rate (HR) >130 beats/min (bpm), respiratory rate >30/min, mean arterial pressure <55 mm Hg, oxygen saturation <90%, or nurse concern; or nonsevere (required 2 abnormal values): temperature >38 or <36°C, blood pressure >160/110 or <85/45 mm Hg, HR >110 or <50 bpm, respiratory rate >24 or <10/min, oxygen saturation <93%, fetal HR >160 bpm, altered mental status, or disproportionate pain. Within each group, recommended management or assessment was also provided. Outcome measures were Centers for Disease Control and Prevention (CDC)-defined severe maternal morbidity, composite maternal morbidity, and intensive care unit (ICU) admissions. Two time intervals were used to analyze the effect of the MEWT tool: a 24-month baseline control period and a 13-month MEWT study period. To determine that the findings noted were not simply changes that would have occurred without the utilization of the early warning tool, we also compared a control population from nonpilot sites during the same baseline and 13-month time periods.

RESULTS

There were 36,832 deliveries at the pilot sites (24,221 pre- and 12,611 post-MEWT testing) and 146,359 at the nonpilot sites (95,718 pre- and 50,641 post-MEWT testing) during the 2 study time periods. Use of the MEWT tool resulted in significant reductions in CDC severe maternal morbidity (P < 0.01) and composite morbidity (P < 0.01). ICU admissions were unchanged. At nonpilot sites CDC severe maternal morbidity, composite morbidity, and ICU admissions were unchanged between baseline and the post-MEWT testing time period.

CONCLUSION

The use of the MEWT tool in this study, designed to address 4 of the most common causes of maternal morbidity, as well as provide assessment and management recommendations, resulted in significant improvement in maternal morbidity. The variation in hospital delivery services at the pilot sites suggests that this maternal early warning tool would be suitable for use in the majority of maternity centers in the United States.

摘要

背景

在过去20年里,美国孕产妇死亡率持续上升。孕产妇发病率也影响着越来越多的美国女性。许多国家和州级组织建议使用孕产妇早期预警工具来解决这一问题。仅有有限的数据表明,使用这类临床评估工具可降低孕产妇发病率。

目的

我们试图确定实施特定临床路径的孕产妇早期预警触发(MEWT)工具是否能降低孕产妇发病率。

研究设计

该工具由内部开发,并作为试点项目前瞻性地在一个大型医院系统的29家医院中的6家实施。主要目标是对疑似临床病情恶化的患者进行早期评估和治疗。该工具涉及孕产妇发病最常见的4个领域:败血症(脓毒症)、心肺功能障碍、先兆子痫 - 高血压和出血。若要判定为阳性,触发情况需持续超过20分钟,并定义为严重(单一异常值):孕产妇心率(HR)>130次/分钟(bpm)、呼吸频率>30次/分钟、平均动脉压<55毫米汞柱、血氧饱和度<90%,或护士关注;或非严重(需要2个异常值):体温>38或<36°C、血压>160/110或<85/45毫米汞柱、HR>110或<50 bpm、呼吸频率>24或<10次/分钟、血氧饱和度<93%、胎儿心率>160 bpm、精神状态改变或疼痛异常。在每组中,还提供了推荐的管理或评估措施。结局指标为疾病控制与预防中心(CDC)定义的严重孕产妇发病率、综合孕产妇发病率和重症监护病房(ICU)入院情况。使用两个时间间隔来分析MEWT工具的效果:24个月的基线对照期和13个月的MEWT研究期。为确定所观察到的结果并非仅仅是在未使用早期预警工具情况下也会发生的变化,我们还比较了同一基线期和13个月时间段内非试点医院的对照人群。

结果

在两个研究时间段内,试点医院有36,832例分娩(MEWT测试前24,221例,测试后12,611例),非试点医院有146,359例分娩(MEWT测试前95,718例,测试后50,641例)。使用MEWT工具使CDC定义的严重孕产妇发病率(P < 0.01)和综合发病率(P < 0.01)显著降低。ICU入院率未变。在非试点医院,CDC定义的严重孕产妇发病率、综合发病率和ICU入院率在基线期和MEWT测试后时间段之间未发生变化。

结论

本研究中使用的MEWT工具旨在解决孕产妇发病的4个最常见原因,并提供评估和管理建议,显著改善了孕产妇发病率。试点医院分娩服务的差异表明,这种孕产妇早期预警工具适用于美国大多数产科中心。

相似文献

1
Use of Maternal Early Warning Trigger tool reduces maternal morbidity.使用孕产妇早期预警触发工具可降低孕产妇发病率。
Am J Obstet Gynecol. 2016 Apr;214(4):527.e1-527.e6. doi: 10.1016/j.ajog.2016.01.154. Epub 2016 Feb 28.
2
Implementation and Evaluation of an Electronic Maternal Early Warning Trigger Tool to Reduce Maternal Morbidity.实施和评估电子产妇早期预警触发工具以减少产妇发病率。
Am J Perinatol. 2021 Jul;38(9):869-879. doi: 10.1055/s-0040-1721715. Epub 2020 Dec 27.
3
Baseline assessment of a hospital-specific early warning trigger system for reducing maternal morbidity.针对降低孕产妇发病率的医院特定早期预警触发系统的基线评估。
Int J Gynaecol Obstet. 2016 Mar;132(3):337-41. doi: 10.1016/j.ijgo.2015.07.036. Epub 2015 Dec 2.
4
Eclampsia reduction with maternal early warning trigger tool.使用孕产妇早期预警触发工具降低子痫发病率
Pregnancy Hypertens. 2024 Mar;35:6-11. doi: 10.1016/j.preghy.2023.11.007. Epub 2023 Dec 2.
5
Performance of the Obstetric Early Warning Score in critically ill patients for the prediction of maternal death.产科早期预警评分在危重症患者中预测孕产妇死亡的效能
Am J Obstet Gynecol. 2017 Jan;216(1):58.e1-58.e8. doi: 10.1016/j.ajog.2016.09.103. Epub 2016 Oct 15.
6
Comparison of the efficacy for early warning systems in predicting obstetric critical illness.比较预测产科危急重症的预警系统的疗效。
Eur J Obstet Gynecol Reprod Biol. 2024 May;296:327-332. doi: 10.1016/j.ejogrb.2024.03.025. Epub 2024 Mar 19.
7
Obstetric early warning system to predict maternal morbidity of pre-eclampsia, postpartum hemorrhage and infection after birth in high-risk women: a prospective cohort study.预测高危孕妇子痫前期、产后出血及产后感染孕产妇发病率的产科早期预警系统:一项前瞻性队列研究
Midwifery. 2021 Aug;99:103015. doi: 10.1016/j.midw.2021.103015. Epub 2021 Apr 15.
8
A Validation Study of Maternal Early Warning Systems: A Retrospective Cohort Study.产妇早期预警系统验证研究:一项回顾性队列研究。
Am J Perinatol. 2019 Sep;36(11):1106-1114. doi: 10.1055/s-0039-1681097. Epub 2019 Mar 11.
9
Early standardized treatment of critical blood pressure elevations is associated with a reduction in eclampsia and severe maternal morbidity.早期对严重血压升高进行标准化治疗可降低子痫和严重孕产妇发病率。
Am J Obstet Gynecol. 2017 Apr;216(4):415.e1-415.e5. doi: 10.1016/j.ajog.2017.01.008. Epub 2017 Jan 30.
10
Reduction of severe maternal morbidity from hemorrhage using a state perinatal quality collaborative.利用州围产期质量协作减少因出血导致的严重产妇发病率。
Am J Obstet Gynecol. 2017 Mar;216(3):298.e1-298.e11. doi: 10.1016/j.ajog.2017.01.017. Epub 2017 Jan 30.

引用本文的文献

1
Clinical Scores of Peripartum Patients Admitted to Maternity Wards Compared to the ICU: A Systematic Review and Meta-Analysis.与重症监护病房相比,产科病房收治的围产期患者的临床评分:一项系统评价和荟萃分析
J Clin Med. 2025 Jul 18;14(14):5113. doi: 10.3390/jcm14145113.
2
A Multicenter Study in Northern Italy to Evaluate the Impact of a Sepsis Bundle in Obstetric Settings: The SOS Study.意大利北部一项评估脓毒症集束化治疗在产科环境中影响的多中心研究:SOS研究。
Open Forum Infect Dis. 2025 Jun 16;12(7):ofaf337. doi: 10.1093/ofid/ofaf337. eCollection 2025 Jul.
3
Sepsis and Septic Shock During Pregnancy and Postpartum.
妊娠期和产后的脓毒症及脓毒性休克
Obstet Gynecol. 2025 Jun 26;146(2):207-222. doi: 10.1097/AOG.0000000000005991.
4
Development and Implementation of an Automated Electronic Maternal Early Warning System (E-MEWS) in a Level IV Obstetric Unit.四级产科单位中自动化电子孕产妇早期预警系统(E-MEWS)的开发与实施
Cureus. 2025 May 24;17(5):e84740. doi: 10.7759/cureus.84740. eCollection 2025 May.
5
Severe maternal morbidity in Louisiana by race, rurality, poverty, and availability of care.路易斯安那州严重孕产妇发病率与种族、农村地区、贫困及医疗可及性的关系
Public Health. 2025 Sep;246:105824. doi: 10.1016/j.puhe.2025.105824. Epub 2025 Jun 20.
6
Maternal Near Miss Morbidity and Mortality: An Audit Analysis of 10 Years From a Private Tertiary Care Obstetric Center.孕产妇严重并发症及死亡情况:来自一家私立三级产科中心的10年审计分析
Cureus. 2025 Apr 10;17(4):e82031. doi: 10.7759/cureus.82031. eCollection 2025 Apr.
7
Differences in Characteristics of Peripartum Patients Who Did and Did Not Require an Upgrade to the Intensive Care Unit: A Propensity Score Matching Study.分娩期需要和不需要升级到重症监护病房的患者特征差异:一项倾向评分匹配研究。
Medicina (Kaunas). 2025 Jan 20;61(1):163. doi: 10.3390/medicina61010163.
8
Obstetric-specific compared to general early warning system for predicting severe postpartum maternal morbidity.与通用早期预警系统相比,用于预测严重产后孕产妇发病情况的产科特定早期预警系统。
Biomol Biomed. 2025 May 8;25(7):1517-1521. doi: 10.17305/bb.2024.11679.
9
Maternal sepsis: background, diagnosis and management.孕产妇败血症:背景、诊断与管理
BJA Educ. 2024 Nov;24(11):389-398. doi: 10.1016/j.bjae.2024.06.004. Epub 2024 Aug 13.
10
Clinical decision support systems for maternity care: a systematic review and meta-analysis.用于产科护理的临床决策支持系统:一项系统评价与荟萃分析
EClinicalMedicine. 2024 Sep 5;76:102822. doi: 10.1016/j.eclinm.2024.102822. eCollection 2024 Oct.