Wang Wenhui, Wei Jie, Feng Dingqing, Ling Bin
Department of Obstetrics and Gynecology, China-Japan Friendship Hospital, Beijing, China.
State Key Laboratory of Chemical Resource Engineering, College of Chemistry, Beijing University of Chemical Technology, Beijing, China.
Front Pharmacol. 2024 Mar 8;15:1344855. doi: 10.3389/fphar.2024.1344855. eCollection 2024.
Ovarian cancer remains to be a significant cause of global cancer-related mortality. In recent years, there has been a surge of studies in investigating the application of nanomaterials in the diagnosis and treatment of ovarian cancer. This study aims to conduct a comprehensive bibliometric analysis regarding nanomaterial-based researches on ovarian cancer to evaluate the current state and emerging patterns in this field. A thorough literature search on the Web of Science Core Collection database was conducted to identify articles focused on nanomaterial-based ovarian cancer researches. The studies that met the inclusion criteria were selected for further analysis. VOSviewer and CiteSpace were applied for the bibliometric and visual analyses of the selected publications. A total of 2,426 studies were included in this study. The number of annual publications showed a consistent upward trend from 2003 to 2023. Notably, China, the United States, and India have emerged as the leading contributors in this field, accounting for 37.39%, 34.04%, and 5.69% of the publications, respectively. The Chinese Academy of Sciences and Anil K. Sood were identified as the most influential institution and author, respectively. Furthermore, the International Journal of Nanomedicine was the most frequently cited journal. In terms of the research focus, significant attention has been directed towards nanomaterial-related drug delivery, while the exploration of immunogenic cell death and metal-organic frameworks represented recent areas of interest. Through comprehensive analyses, an overview of current research trends and emerging areas of interest regarding the application of nanomaterials in ovarian cancer was illustrated. These findings offered valuable insights into the status and future directions of this dynamic field.
卵巢癌仍然是全球癌症相关死亡的一个重要原因。近年来,在研究纳米材料在卵巢癌诊断和治疗中的应用方面,研究数量激增。本研究旨在对基于纳米材料的卵巢癌研究进行全面的文献计量分析,以评估该领域的现状和新出现的模式。我们在科学网核心合集数据库上进行了全面的文献检索,以确定专注于基于纳米材料的卵巢癌研究的文章。选择符合纳入标准的研究进行进一步分析。VOSviewer和CiteSpace被用于对所选出版物进行文献计量和可视化分析。本研究共纳入2426项研究。从2003年到2023年,年度出版物数量呈持续上升趋势。值得注意的是,中国、美国和印度已成为该领域的主要贡献者,分别占出版物的37.39%、34.04%和5.69%。中国科学院和阿尼尔·K·苏德分别被确定为最具影响力的机构和作者。此外,《国际纳米医学杂志》是被引用频率最高的期刊。在研究重点方面,对与纳米材料相关的药物递送给予了极大关注,而免疫原性细胞死亡和金属有机框架的探索代表了近期的研究热点。通过综合分析,阐述了纳米材料在卵巢癌应用方面当前的研究趋势和新出现的研究热点概况。这些发现为这一动态领域的现状和未来方向提供了有价值的见解。