Shu Chunxi, Yin Xinyang, Zhong Qin, Cheng Ming
Department of Sports Medicine, Orthopaedic Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, China.
Heliyon. 2024 Aug 20;10(17):e36541. doi: 10.1016/j.heliyon.2024.e36541. eCollection 2024 Sep 15.
As the population ages, the socio-economic impact of osteoarthritis (OA) is becoming increasingly significant. In recent years, there has been a growing focus on the design and development of nanomaterials for diagnosing and treating OA. This study aims to comprehensively evaluate the current status and trends in the application of nanomaterials in OA through bibliometric analysis and provide a review.
Studies on nanomaterials and OA were sourced from the Web of Science Core Collection (WoSCC) database, with relevant articles selected based on predefined inclusion criteria. Quantitative and visual analyses of the included publications were conducted using tools such as VOSviewer, and GraphPad Prism 9.5.0.
A total of 532 publications were included in this study. The number of annual publications has increased steadily from 2006 to 2023. China, the United States, and South Korea are the leading countries in this field. Shanghai Jiao Tong University and Li Zheng are recognized as the most influential institutions and authors, respectively. Biomaterials is the most frequently published and cited journal. Current research primarily focuses on drug delivery and the anti-inflammatory and antioxidant properties of nanomaterials. Recent research hotspots include mesoporous silica nanoparticles, electrostatic interaction, and injectable hydrogels.
In this study, we summarised the annual publication trends and identified the most influential countries, institutions, authors, journals, and current research and development trends in the application of nanomaterials for OA.
随着人口老龄化，骨关节炎（OA）的社会经济影响日益显著。近年来，用于诊断和治疗OA的纳米材料的设计和开发受到越来越多的关注。本研究旨在通过文献计量分析全面评估纳米材料在OA应用中的现状和趋势，并提供综述。
从科学网核心合集（WoSCC）数据库中获取有关纳米材料和OA的研究，根据预定义的纳入标准选择相关文章。使用VOSviewer和GraphPad Prism 9.5.0等工具对纳入的出版物进行定量和可视化分析。
本研究共纳入532篇出版物。从2006年到2023年，年出版物数量稳步增加。中国、美国和韩国是该领域的领先国家。上海交通大学和李政分别被认为是最具影响力的机构和作者。《生物材料》是发表和被引用频率最高的期刊。当前的研究主要集中在纳米材料的药物递送以及抗炎和抗氧化特性。近期的研究热点包括介孔二氧化硅纳米颗粒、静电相互作用和可注射水凝胶。
在本研究中，我们总结了年出版物趋势，并确定了纳米材料在OA应用中最具影响力的国家、机构、作者、期刊以及当前的研发趋势。
