Kumar Naina, Mangla Mishu
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Bibinagar, Hyderabad, Telangana, 508126, India.
Cancer Chemother Pharmacol. 2025 Jan 4;95(1):18. doi: 10.1007/s00280-024-04747-4.
Gynecological cancers, such as ovarian, cervical, and endometrial malignancies, are notoriously challenging due to their intricate biology and the critical need for precise diagnostic and therapeutic approaches. In recent years, groundbreaking advances in nanotechnology and nanobots have emerged as game-changers in this arena, offering the promise of a new paradigm in cancer management. This comprehensive review delves into the revolutionary potential of these technologies, showcasing their ability to transform the landscape of gynecological oncology.
A systematic literature search spanning from March 2005 to August 2024 was conducted using major databases such as PubMed, Google Scholar, and Scopus. Keywords included "nanotechnology," "nanobots," "gynecological cancers," "ovarian cancer," "cervical cancer," and "endometrial cancer." Relevant articles published in English were selected based on their focus on nanotechnology and nanobots in the diagnosis, treatment, and management of gynecological cancers. The findings were synthesized to present a coherent overview of how nanotechnology and nanobots are reshaping gynecological cancer management. The review highlights key innovations, current applications, and future directions for research and clinical implementation.
The integration of nanotechnology and nanobots in gynecological cancer management represents a groundbreaking shift in the field. Recent advancements in nanoscale materials and robotic technology offer unprecedented opportunities for precision diagnosis, targeted drug delivery, and innovative therapeutic approaches. Despite promising developments, challenges such as biocompatibility, safety, and regulatory issues remain. Continued research and clinical trials are essential to overcome these hurdles and fully realize the potential of nanotechnology and nanobots.
妇科癌症，如卵巢癌、宫颈癌和子宫内膜癌，因其复杂的生物学特性以及对精确诊断和治疗方法的迫切需求而极具挑战性。近年来，纳米技术和纳米机器人取得了突破性进展，成为这一领域的变革者，为癌症管理带来了新范式的希望。这篇全面综述深入探讨了这些技术的革命性潜力，展示了它们改变妇科肿瘤学格局的能力。
使用PubMed、谷歌学术和Scopus等主要数据库，对2005年3月至2024年8月期间的文献进行了系统检索。关键词包括“纳米技术”“纳米机器人”“妇科癌症”“卵巢癌”“宫颈癌”和“子宫内膜癌”。根据文章对纳米技术和纳米机器人在妇科癌症诊断、治疗和管理方面的关注，筛选出以英文发表的相关文章。对研究结果进行综合分析，以连贯地概述纳米技术和纳米机器人如何重塑妇科癌症管理。该综述突出了关键创新、当前应用以及研究和临床实施的未来方向。
纳米技术和纳米机器人在妇科癌症管理中的整合代表了该领域的突破性转变。纳米级材料和机器人技术的最新进展为精确诊断、靶向给药和创新治疗方法提供了前所未有的机会。尽管取得了有前景的进展，但生物相容性、安全性和监管问题等挑战依然存在。持续的研究和临床试验对于克服这些障碍并充分实现纳米技术和纳米机器人的潜力至关重要。
