Singh Pooja, Semwal Prabhakar, Gargi Baby, Painuli Sakshi, Aschner Michael, Alsharif Khalaf F, Khan Haroon, Bachheti Rakesh Kumar, Worku Limenew Abate
Department of Biotechnology, Graphic Era (Deemed to be University), 566/6 Bell Road, Clement Town, Dehradun, 248002, Uttarakhand, India.
Research and Development Cell, Graphic Era Hill University, Society Area, Dehradun, 248002, Uttarakhand, India.
Discov Oncol. 2024 Oct 9;15(1):539. doi: 10.1007/s12672-024-01332-2.
Lung cancer ranks as one of the most rapidly growing malignancies. Which is characterized by its poor prognosis and a low survival rate due to late diagnosis and limited efficacy of conventional treatments. In recent years nanotechnology has emerged as a promising frontier in the management of lung cancer, presenting novel strategies to enhance drug administration, improve therapeutic efficiency, and mitigate side effects. This research comprehensively evaluates the current state and research trends concerning the application of nanomaterials in lung cancer through bibliometric analysis.
We employed a systematic approach by retrieving studies from the Scopus database that focused on nanomaterials and lung cancer between 2003 and 2023. Subsequently, we carefully selected relevant articles based on predetermined inclusion criteria. The selected publications were then subjected to bibliometric and visual analysis using softwares such as VOSviewer and Biblioshiny.
A total of 3523 studies that meet inclusion criteria were selected for bibliometric analysis. We observed a progressive increase in the number of annual publications from 2003 to 2023, indicating the growing interest in this field. According to our analysis, China is the primary contributor to publication output among the countries. The "Ministry of Education of the People's Republic of China" was the most influential institution. Among the authors, "Dr. Jack A. Roth" and "Dr. Huang Leaf" had the highest number of publications and cited publications, respectively. The "International Journal of Nanomedicine" was found to be the most prolific journal in this field. Additionally, "Biomaterials" emerged as the most cited journal. Through keyword analysis, we identified five main research themes and future research directions; nono-immunotherapy and green synthesis are the hot topics in this research field.
Our study summarized the key characteristics of publications in this field and identified the most influential countries, institutions, authors, journals, hot topics, and trends related to the application of nanomaterials in lung cancer. These findings contribute to the existing body of knowledge and serve as a foundation for future research endeavors in this area. More effective efforts are needed in this field to reduce the burden of lung cancer and help achieve the United Nation's Sustainable Development Goals.
肺癌是增长最为迅速的恶性肿瘤之一。其特点是预后较差，由于诊断较晚和传统治疗效果有限，生存率较低。近年来，纳米技术已成为肺癌治疗领域一个充满前景的前沿领域，提供了增强药物给药、提高治疗效率和减轻副作用的新策略。本研究通过文献计量分析全面评估了纳米材料在肺癌应用方面的现状和研究趋势。
我们采用系统的方法，从Scopus数据库中检索2003年至2023年间专注于纳米材料与肺癌的研究。随后，我们根据预定的纳入标准仔细筛选相关文章。然后使用VOSviewer和Biblioshiny等软件对所选出版物进行文献计量和可视化分析。
共选择了3523项符合纳入标准的研究进行文献计量分析。我们观察到2003年至2023年每年的出版物数量呈逐步上升趋势，表明该领域的关注度不断增加。根据我们的分析，中国是各国中出版物产出的主要贡献者。中华人民共和国教育部是最具影响力的机构。在作者中，“杰克·A·罗斯博士”和“黄叶博士”分别拥有最多的出版物数量和被引出版物数量。《国际纳米医学杂志》被发现是该领域发表文章最多的期刊。此外，《生物材料》是被引次数最多的期刊。通过关键词分析，我们确定了五个主要研究主题和未来研究方向；纳米免疫疗法和绿色合成是该研究领域的热门话题。
我们的研究总结了该领域出版物的关键特征，确定了与纳米材料在肺癌应用相关的最具影响力的国家、机构、作者、期刊、热门话题和趋势。这些发现为现有知识体系做出了贡献，并为该领域未来的研究工作奠定了基础。该领域需要做出更有效的努力，以减轻肺癌负担，并有助于实现联合国可持续发展目标。
