Rashid Sameeah Abdulrahman
Department of Surgery, College of Medicine, Hawler Medical University, Erbil, Iraq.
Radiol Res Pract. 2024 Mar 15;2024:7178920. doi: 10.1155/2024/7178920. eCollection 2024.
This multicenter cross-sectional study was performed on two groups of adults (nondiabetes and type 2 diabetes) of various ages, sexes, and body mass index (BMI). CIMT for each side was measured at three segments using high-resolution ultrasound, and the mean of both sides was determined. Comparison was made between each group, and the association of CIMT with each of age, sex, BMI, serum vitamin D status, smoking, and physical activity status was studied. The chi-square test was used to compare categorical data, and binary logistic regression was utilized to ascertain the relationship between CIMT and the study variables.
A significant difference was observed between the CIMT of the diabetes and nondiabetes group, average CIMT was 0.82 ± 0.23 mm vs. 1.12 ± 0.24 mm for the nondiabetes and diabetes group, respectively, with value <0.005. No significant correlation was observed between serum vitamin D level and CIMT neither in the study group as a whole nor in either subgroup; however, a significant association was observed between CIMT with each of age, sex, BMI, smoking, and physical activity status.
Ultrasound is a sensitive tool for CIMT evaluation. Diabetes has a 5.4-fold higher risk of having high CIMT. Serum vitamin D level showed no significant influence on CIMT. Smoking, BMI, and physical activity are among the modifiable risk factors with significant influence on CIMT.
本多中心横断面研究针对两组不同年龄、性别和体重指数（BMI）的成年人（非糖尿病组和2型糖尿病组）进行。使用高分辨率超声在三个节段测量每侧的颈动脉内膜中层厚度（CIMT），并确定两侧的平均值。对每组进行比较，并研究CIMT与年龄、性别、BMI、血清维生素D状态、吸烟和身体活动状态之间的关联。采用卡方检验比较分类数据，并使用二元逻辑回归确定CIMT与研究变量之间的关系。
糖尿病组和非糖尿病组的CIMT之间观察到显著差异，非糖尿病组和糖尿病组的平均CIMT分别为0.82±0.23毫米和1.12±0.24毫米，P值<0.005。在整个研究组或任何一个亚组中，血清维生素D水平与CIMT之间均未观察到显著相关性；然而，CIMT与年龄、性别、BMI、吸烟和身体活动状态之间均观察到显著关联。
超声是评估CIMT的敏感工具。糖尿病患者CIMT升高的风险高5.4倍。血清维生素D水平对CIMT无显著影响。吸烟、BMI和身体活动是对CIMT有显著影响的可改变风险因素。
