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酒精使用障碍患者并发脑出血的坏血病一例。

A Case of Scurvy Associated With Intracerebral Hemorrhage in a Patient With Alcohol Use Disorder.

作者信息

Masuda Yohei, Saigusa Kuniyasu, Norisue Yasuhiro

机构信息

Department of Emergency and Critical Care Medicine, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu, JPN.

Department of Internal Medicine, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu, JPN.

出版信息

Cureus. 2024 Feb 23;16(2):e54777. doi: 10.7759/cureus.54777. eCollection 2024 Feb.

DOI:10.7759/cureus.54777
PMID:38523974
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10961150/
Abstract

Vitamin C deficiency, also known as scurvy, causes abnormalities in connective tissues and varied symptoms. We describe a patient with putaminal hemorrhage, a very rare presentation of scurvy. A 39-year-old man presented with weakness in the left arm and left leg. Right putaminal hemorrhage was initially diagnosed, and he underwent evacuation of the intracerebral hemorrhage. Scurvy was suspected when repeated physical examinations revealed a bleeding tendency and multiple untreated dental caries, missing teeth, and gingivitis. A diagnosis of scurvy was further supported by the patient's history of smoking, alcohol use disorder, poor diet, and low plasma vitamin C concentration. After receiving oral nutritional supplementation including vitamin C, the bleeding tendency quickly improved. This case highlights the importance of including scurvy in a differential diagnosis for patients with bleeding tendencies, especially those with a poor diet or unknown dietary history. Empirical administration of vitamin C is a reasonable treatment.

摘要

维生素C缺乏症,也称为坏血病,会导致结缔组织异常和各种症状。我们描述了一名患有壳核出血的患者,这是坏血病非常罕见的一种表现形式。一名39岁男性出现左臂和左腿无力症状。最初诊断为右侧壳核出血,随后他接受了脑出血清除手术。当反复体格检查发现有出血倾向以及多处未经治疗的龋齿、牙齿缺失和牙龈炎时,怀疑患有坏血病。患者的吸烟史、酒精使用障碍、不良饮食习惯以及低血浆维生素C浓度进一步支持了坏血病的诊断。在接受包括维生素C在内的口服营养补充后,出血倾向迅速改善。该病例强调了在对有出血倾向的患者,尤其是饮食不良或饮食史不明的患者进行鉴别诊断时,将坏血病纳入考虑的重要性。经验性给予维生素C是一种合理的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/503c/10961150/a510e5b2d118/cureus-0016-00000054777-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/503c/10961150/3b45b4eb7700/cureus-0016-00000054777-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/503c/10961150/da6c6cfd4be6/cureus-0016-00000054777-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/503c/10961150/a510e5b2d118/cureus-0016-00000054777-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/503c/10961150/3b45b4eb7700/cureus-0016-00000054777-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/503c/10961150/da6c6cfd4be6/cureus-0016-00000054777-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/503c/10961150/a510e5b2d118/cureus-0016-00000054777-i03.jpg

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本文引用的文献

1
Bifrontal Epidural Hemorrhage Secondary to Scurvy in a 10-Year-Old Boy.一名10岁男孩因坏血病继发双侧额叶硬膜外出血
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Adding an orange to the banana bag: vitamin C deficiency is common in alcohol use disorders.给香蕉袋中加个橙子:维生素 C 缺乏在酒精使用障碍中很常见。
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Serum vitamin C concentration was inversely associated with subsequent 20-year incidence of stroke in a Japanese rural community. The Shibata study.在日本一个农村社区,血清维生素C浓度与随后20年中风发病率呈负相关。柴田研究。
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