Rabab Syeda Abiha, Zaidi Syeda Mahrukh Fatima, Amjad Ayesha, Sattar Maryam
Memon Medical Institute Hospital, Karachi, Pakistan.
Dow University of Health Sciences, Karachi, Pakistan.
SAGE Open Med Case Rep. 2024 Mar 21;12:2050313X241241197. doi: 10.1177/2050313X241241197. eCollection 2024.
Pancreatic cancer is a silent and lethal adversary that often conceals its presence until advanced stages. This report elucidates a distinctive case of a 46-year-old patient with pancreatic tail adenocarcinoma presenting with venous thrombosis, a rare manifestation. The patient's symptoms included severe left leg pain, swelling, and redness, accompanied by weight loss and decreased appetite. Laboratory findings indicated a prothrombotic state, whereas imaging revealed a substantial mass on the tail of the pancreas with hepatic metastasis. Elevated cancer antigen 19-9 and carcinoembryonic antigen supported the diagnosis which was confirmed by a liver biopsy. This case underscores the diagnostic challenges posed by pancreatic cancer, particularly in the tail, emphasizing the need for early detection. The intricate interplay between metastasis and thrombosis complicates the clinical landscape, requiring a comprehensive approach to management.
胰腺癌是一个隐匿且致命的对手，常常在晚期才显露其踪迹。本报告阐述了一例独特病例，一名46岁患有胰尾腺癌的患者出现静脉血栓形成，这是一种罕见的表现。患者的症状包括左腿剧痛、肿胀和发红，伴有体重减轻和食欲下降。实验室检查结果表明处于血栓前状态，而影像学检查显示胰腺尾部有一个巨大肿块并伴有肝转移。癌抗原19-9和癌胚抗原升高支持了诊断，肝活检证实了这一诊断。该病例凸显了胰腺癌尤其是胰尾癌所带来的诊断挑战，强调了早期检测的必要性。转移与血栓形成之间复杂的相互作用使临床情况变得复杂，需要采取综合的管理方法。
