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英国北部纬度地区职业足球运动员的循环总25(羟)维生素D和计算得出的游离25(羟)维生素D

Circulating total 25(OH)D and calculated free 25(OH)D in professional academy footballers at a northerly latitude in the UK.

作者信息

Bowles Simon D, Basu Subhashis, Ranchordas Mayur K, Simper Trevor, Lynn Anthony

机构信息

Food Group, Sheffield Business School, Sheffield Hallam University, Sheffield, UK.

Sheffield Teaching Hospitals NHS Trust, Sheffield, UK.

出版信息

Biol Sport. 2024 Mar;41(2):201-208. doi: 10.5114/biolsport.2024.131822. Epub 2023 Nov 10.

DOI:10.5114/biolsport.2024.131822
PMID:38524830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10955734/
Abstract

There is limited data on the vitamin D status of UK-based professional academy footballers. Therefore, the objective of this study was to report total 25(OH)D, free 25(OH)D and free 1, 25(OH)D at the end of the winter (March) and summer periods (October) in a cohort (n = 27) of professional academy footballers in northern England. Blood samples were collected to measure total 25(OH)D, parathyroid hormone, vitamin D binding protein, albumin and calcium. Free 25(OH)D and 1, 25(OH)D were calculated. Dietary vitamin D intake and retrospective summer sunlight exposure were also collected. At the end of winter, 2/27 (7.4%) players were vitamin D deficient (25(OH)D < 30 nmol/l) and 11/27 (40.7%) were insufficient (25(OH)D > 30 nmol/l < 50 nmol/l). By the end of summer, none were deficient but 3/14 (21.4%) were still insufficient. Median total 25(OH)D (82.2 nmol/l [IQR: 50.3-90.2] vs. 54.2 nmol/l [IQR: 36.8-71.9]; P = .02), free 25(OH)D (25.8 pmol/l [IQR: 15.1-33.1] vs. 13.2 pmol/l [IQR: 9.0-14.9]; P = .005) and free 1, 25(OH)D (389 fmol/l [IQR: 209-594] vs. 212 fmol/l [IQR: 108-278]; P = .034) were significantly higher at the end of summer than the end of winter. At the end of winter, free 25(OH)D was lower (P = .003) in those vitamin D insufficient (8.8 pmol/l [IQR: 5.5-11.8]) vs. sufficient (13.7 pmol/l [IQR: 12.0-17.0]). There was a high prevalence of vitamin D insufficiency at the end of the winter. Free 25(OH)D was also lower at the winter timepoint and in players that were insufficient vs. sufficient.

摘要

关于英国职业足球学院球员的维生素D状况的数据有限。因此,本研究的目的是报告英格兰北部一组职业足球学院球员(n = 27)在冬季末(3月)和夏季末(10月)的总25(OH)D、游离25(OH)D和游离1,25(OH)D水平。采集血样以测量总25(OH)D、甲状旁腺激素、维生素D结合蛋白、白蛋白和钙。计算游离25(OH)D和1,25(OH)D。还收集了饮食中维生素D的摄入量以及回顾性的夏季阳光暴露情况。在冬季末,2/27(7.4%)的球员维生素D缺乏(25(OH)D < 30 nmol/l),11/27(40.7%)的球员维生素D不足(25(OH)D > 30 nmol/l < 50 nmol/l)。到夏季末,没有人缺乏维生素D,但仍有3/14(21.4%)的球员维生素D不足。夏季末的总25(OH)D中位数(82.2 nmol/l [四分位间距:50.3 - 90.2] 对比 54.2 nmol/l [四分位间距:36.8 - 71.9];P = .02)、游离25(OH)D中位数(25.8 pmol/l [四分位间距:15.1 - 33.1] 对比 13.2 pmol/l [四分位间距:9.0 - 14.9];P = .005)和游离1,25(OH)D中位数(389 fmol/l [四分位间距:209 - 594] 对比 212 fmol/l [四分位间距:108 - 278];P = .034)均显著高于冬季末。在冬季末,维生素D不足的球员(8.8 pmol/l [四分位间距:5.5 - 11.8])的游离25(OH)D水平低于充足的球员(13.7 pmol/l [四分位间距:12.0 - 17.0])(P = .003)。在冬季末,维生素D不足的患病率很高。在冬季这个时间点以及维生素D不足的球员中,游离25(OH)D水平也较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8207/10955734/9fcec02b61dc/JBS-41-51586-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8207/10955734/eacbafce0d88/JBS-41-51586-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8207/10955734/87654760df6b/JBS-41-51586-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8207/10955734/9fcec02b61dc/JBS-41-51586-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8207/10955734/eacbafce0d88/JBS-41-51586-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8207/10955734/87654760df6b/JBS-41-51586-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8207/10955734/9fcec02b61dc/JBS-41-51586-g003.jpg

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