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药学住院医师科研项目发表情况:系统评价和荟萃分析。

Publication of pharmacy resident research projects: A systematic review and meta-analysis.

机构信息

Acute Care Pharmacy Services, University of Kentucky Healthcare, Lexington, KY, and Department of Pharmacy Practice and Science, University of Kentucky College of Pharmacy, Lexington, KY, USA.

Department of Pharmacy, University of Chicago Medicine, Chicago, IL, USA.

出版信息

Am J Health Syst Pharm. 2024 Aug 12;81(16):713-722. doi: 10.1093/ajhp/zxae091.

DOI:10.1093/ajhp/zxae091
PMID:38530288
Abstract

PURPOSE

Pharmacy residents often aspire to develop research skills through conducting a research project. Project publication rates among pharmacy residents are variable and at times low; however, previous studies have been limited to specific geographic regions and timeframes. This study sought to conduct a systematic review and meta-analysis to determine the proportion of pharmacy resident research projects published in the peer-reviewed literature.

METHODS

A systematic review of PubMed MEDLINE, Embase, and the Web of Science Core Collection was performed from database inception to May 25, 2023. Articles were included if they were full-text, peer-reviewed manuscripts of original research presenting observational data regarding pharmacy resident research project publication rates. Data extraction and assessment of risk of bias were conducted by 2 independent reviewers. A proportional meta-analysis using a random effects model of the included studies was conducted to generate a pooled, overall proportion.

RESULTS

The search yielded 5,225 records and 12 articles that met the inclusion criteria. All studies were retrospective and observational. Risk of selection and cohort identification biases was "high," whereas that of detection and timeframe biases was "low." The included studies represented 6,990 resident research projects, 777 of which were published in the peer-reviewed literature. Publication rates across individual studies ranged from 1.8% to 36.2%. The pooled proportion (scale of 0 to 1) of projects published was 0.13 (95% CI, 0.09-0.19).

CONCLUSION

Pharmacy resident research project publication rates are low at 13%. Furthermore, studies reporting project publication rates over time suggest a neutral or negative trend in publication rates despite an exponential increase in the number of pharmacy residents.

摘要

目的

药剂学住院医师通常希望通过开展研究项目来培养研究技能。药剂学住院医师的项目发表率各不相同,有时较低;然而,以前的研究仅限于特定的地理区域和时间框架。本研究旨在进行系统评价和荟萃分析,以确定在同行评议文献中发表的药剂学住院医师研究项目的比例。

方法

从数据库建立到 2023 年 5 月 25 日,对 PubMed MEDLINE、Embase 和 Web of Science Core Collection 进行了系统评价。如果全文为同行评审的原始研究手稿,报告了关于药剂学住院医师研究项目发表率的观察数据,则纳入研究。由 2 名独立评审员进行数据提取和偏倚风险评估。使用纳入研究的随机效应模型进行比例荟萃分析,以生成汇总的总体比例。

结果

搜索产生了 5225 条记录和 12 篇符合纳入标准的文章。所有研究均为回顾性和观察性研究。选择和队列识别偏倚的风险为“高”,而检测和时间框架偏倚的风险为“低”。纳入的研究代表了 6990 项住院医师研究项目,其中 777 项在同行评议文献中发表。个别研究的发表率范围为 1.8%至 36.2%。发表项目的汇总比例(0 到 1 的比例)为 0.13(95%CI,0.09-0.19)。

结论

药剂学住院医师研究项目的发表率较低,为 13%。此外,报告项目发表率随时间变化的研究表明,尽管药剂学住院医师人数呈指数级增长,但发表率呈中性或负向趋势。

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