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优化肠道疾病疫苗试验:全球健康肠道疾病(EFGH)监测研究

Optimizing Vaccine Trials for Enteric Diseases: The Enterics for Global Health (EFGH) Surveillance Study.

作者信息

Vannice Kirsten, MacLennan Calman Alexander, Long Jessica, Steele Andrew Duncan

机构信息

Enterics, Diagnostics, Genomics & Epidemiology, The Bill & Melinda Gates Foundation, Seattle, Washington, USA.

出版信息

Open Forum Infect Dis. 2024 Mar 25;11(Suppl 1):S1-S5. doi: 10.1093/ofid/ofad586. eCollection 2024 Mar.

DOI:10.1093/ofid/ofad586
PMID:38532964
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10962720/
Abstract

In this introductory article, we describe the rationale for the Enterics for Global Health (EFGH) surveillance study, which is largely to optimize the design and implementation of pivotal vaccine trials in the target population of infants and young children living in low- and middle-income countries. Such optimization will ideally lead to a shorter time to vaccine availability in the target population. We also provide a brief description of the articles included in the supplement.

摘要

在这篇介绍性文章中,我们描述了全球健康肠道病原体(EFGH)监测研究的基本原理,该研究主要是为了优化在低收入和中等收入国家婴幼儿目标人群中进行的关键疫苗试验的设计与实施。这种优化理想情况下将缩短目标人群获得疫苗的时间。我们还简要介绍了该增刊中包含的文章。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fea/10962720/e1a3bf1d8a59/ofad586f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fea/10962720/e1a3bf1d8a59/ofad586f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fea/10962720/e1a3bf1d8a59/ofad586f1.jpg

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本文引用的文献

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Open Forum Infect Dis. 2024 Mar 25;11(Suppl 1):S6-S16. doi: 10.1093/ofid/ofad664. eCollection 2024 Mar.
2
The Enterics for Global Health (EFGH) Surveillance Study in Bangladesh.孟加拉国全球健康肠道病原体监测研究(EFGH)
Open Forum Infect Dis. 2024 Mar 25;11(Suppl 1):S76-S83. doi: 10.1093/ofid/ofad653. eCollection 2024 Mar.
3
Quantifying the Cost of Diarrhea in the Enterics for Global Health (EFGH) Surveillance Study.
用于检测人类样本中抗体的13重结合分析方法的开发与特性研究
Open Forum Infect Dis. 2024 Nov 12;11(12):ofae675. doi: 10.1093/ofid/ofae675. eCollection 2024 Dec.
量化肠道疾病腹泻对全球健康监测研究(EFGH)的成本
Open Forum Infect Dis. 2024 Mar 25;11(Suppl 1):S41-S47. doi: 10.1093/ofid/ofad575. eCollection 2024 Mar.
4
Detection and Molecular Serotyping With a Customized TaqMan Array Card in the Enterics for Global Health (EFGH): Surveillance Study.利用定制的TaqMan阵列卡对肠道细菌进行检测和分子血清分型以促进全球健康(EFGH):监测研究
Open Forum Infect Dis. 2024 Mar 25;11(Suppl 1):S34-S40. doi: 10.1093/ofid/ofad574. eCollection 2024 Mar.
5
The Enterics for Global Health (EFGH) Surveillance Study in The Gambia.冈比亚的全球健康肠道病原体监测研究(EFGH)
Open Forum Infect Dis. 2024 Mar 25;11(Suppl 1):S84-S90. doi: 10.1093/ofid/ofae049. eCollection 2024 Mar.
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Exploring Natural Immune Responses to Exposure Using Multiplex Bead Assays on Dried Blood Spots in High-Burden Countries: Protocol From a Multisite Diarrhea Surveillance Study.在高负担国家利用干血斑多重微珠分析探索暴露后的天然免疫反应:一项多地点腹泻监测研究方案
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