冈比亚的全球健康肠道病原体监测研究（EFGH）
The Enterics for Global Health (EFGH) Surveillance Study in The Gambia.
作者信息
Conteh Bakary, Badji Henry, Jallow Abdoulie F, Karim Mehrab, Manneh Alhagie, Keita Belali, Sarwar Golam, Ceesay Bubacarr E, Jarju Sheikh, Jabang Abdoulie M J, Baldeh Ebrima, Ikumapayi Usman N, Secka Ousman, Antonio Martin, Roca Anna, D'Alessandro Umberto, Kotloff Karen L, Hossain M Jahangir
机构信息
Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, Fajara, The Gambia.
Regional Health Directorate Upper River Region, Ministry of Health and Social Welfare, Basse, The Gambia.
出版信息
Open Forum Infect Dis. 2024 Mar 25;11(Suppl 1):S84-S90. doi: 10.1093/ofid/ofae049. eCollection 2024 Mar.
BACKGROUND
The Gambia, located in West Africa, is one of 7 country sites conducting the Enterics for Global Health (EFGH) Surveillance Study to establish incidence and consequence of -associated medically attended diarrhea among children 6-35 months old.
METHODS
Here we describe the study site and research experience, sociodemographic characteristics of the study catchment area, facilities of recruitment for diarrhea case surveillance, and known care-seeking behavior for diarrheal illness. We also describe The Gambia's healthcare system and financing, current vaccine schedule and vaccine adaptation, local diarrhea management guidelines and challenges, and antibiotic resistance patterns in the region.
CONCLUSIONS
The EFGH study in The Gambia will contribute to the multisite network of surveillance study and prepare the site for future vaccine trials. In addition, the data produced will inform policy makers about prevention strategies and upcoming vaccine studies among children in this setting.
背景
冈比亚位于西非，是开展全球健康肠道疾病（EFGH）监测研究的7个国家站点之一，该研究旨在确定6至35个月大儿童中与医疗就诊腹泻相关的发病率和后果。
方法
在此，我们描述了研究地点和研究经验、研究集水区的社会人口特征、腹泻病例监测的招募设施以及已知的腹泻疾病就医行为。我们还描述了冈比亚的医疗保健系统和融资情况、当前的疫苗接种计划和疫苗适应性、当地腹泻管理指南和挑战以及该地区的抗生素耐药模式。
结论
冈比亚的EFGH研究将为多站点监测研究网络做出贡献，并为未来的疫苗试验做好准备。此外，所产生的数据将为政策制定者提供有关该环境下儿童预防策略和即将开展的疫苗研究的信息。
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