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肾上腺血管瘤的临床特征

Clinical Characteristics of Adrenal Hemangioma.

作者信息

Zuo Yuzhi, Liang Zhen, Yang Shengmin, Pan Boju, Cheng Sihang, Zhou Zhien, Feng Tianrui, Yan Weigang, Wu Xingcheng

机构信息

Department of Urology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

Department of Pathology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

出版信息

J Endocr Soc. 2024 Mar 20;8(5):bvae041. doi: 10.1210/jendso/bvae041. eCollection 2024 Mar 12.

Abstract

OBJECTIVE

Adrenal hemangioma (AH) is a rare, benign adrenal tumor often detected incidentally by imaging. This retrospective study aimed to investigate the clinical characteristics of AH, including clinical and diagnostic imaging features, to improve the recognition and understanding of AH.

METHODS

We retrospectively analyzed the medical records of patients diagnosed with AH at Peking Union Medical College Hospital between 2008 and 2022. Clinical manifestations, adrenal hormone levels, imaging findings, treatment approaches, and pathological results were collected and analyzed.

RESULTS

Of the 7140 adrenal tumor patients, 40 (0.56%) had AH confirmed postoperatively. The mean age at diagnosis was 53.9 years, with a female predominance. Most (70%) were asymptomatic and diagnosed incidentally. Misdiagnosis before surgery was common, most frequently as pheochromocytoma. Imaging characteristics, especially enhanced computed tomography, revealed distinct features based on tumor size. Surgery was the main treatment, with laparoscopic adrenalectomy preferred.

CONCLUSION

This study elucidates the clinical characteristics of AH, including demographics, diagnostic challenges, and imaging features. AH often presents incidentally and is frequently misdiagnosed preoperatively. Recognizing distinct imaging characteristics and appropriate surgical management can enable accurate diagnosis and optimal treatment.

摘要

目的

肾上腺血管瘤(AH)是一种罕见的肾上腺良性肿瘤,常通过影像学检查偶然发现。本回顾性研究旨在探讨AH的临床特征,包括临床及诊断性影像学特征,以提高对AH的认识和理解。

方法

我们回顾性分析了2008年至2022年期间在北京协和医院诊断为AH的患者的病历。收集并分析了临床表现、肾上腺激素水平、影像学表现、治疗方法及病理结果。

结果

在7140例肾上腺肿瘤患者中,40例(0.56%)术后确诊为AH。确诊时的平均年龄为53.9岁,女性居多。大多数(70%)无症状,偶然被发现。术前误诊很常见,最常误诊为嗜铬细胞瘤。影像学特征,尤其是增强计算机断层扫描,根据肿瘤大小显示出不同特征。手术是主要治疗方法,首选腹腔镜肾上腺切除术。

结论

本研究阐明了AH的临床特征,包括人口统计学、诊断挑战及影像学特征。AH常偶然出现,术前常被误诊。认识到不同的影像学特征及适当的手术管理有助于准确诊断和优化治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e500/10964843/17c0f86f0e72/bvae041f1.jpg

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