Gartaganis Panos S, Natsi Panagiota D, Gartaganis Sotirios P, Koutsoukos Petros G, Helbig Horst
Department of Ophthalmology, 251 Hellenic Air Force General Hospital, 3 Kanellopoulou Ave., Athens 11525, Greece.
Laboratory of Inorganic and Analytical Chemistry, Department of Chemical Engineering, University of Patras and FORTH-ICEHT, Patras, Greece.
Ther Adv Ophthalmol. 2024 Mar 25;16:25158414241237713. doi: 10.1177/25158414241237713. eCollection 2024 Jan-Dec.
We report an unusual, rare case of opacification of the hydrophilic acrylic intraocular lens (IOL) 23 years after the initial surgery with significant visual deterioration. Opacification of the hydrophilic acrylic IOL was primarily due to the formation of folds on the surface of the lens material, and less so due to calcium phosphate deposits. Calcification opacification can be attributed to recent events, as evidenced by deposits of dicalcium phosphate dihydrate (CaHPO2HO) and octacalcium phosphate (CaH(PO)5HO), both of which are transient calcium phosphate phases, converting hydrolytically to the thermodynamically most stable hydroxyapatite (Ca(PO)(OH)). To our knowledge, this case of hydrophilic acrylic IOL opacification is the only one that has been described so late, 23 years after cataract surgery.
我们报告了一例罕见的特殊病例，患者在初次手术后23年，亲水性丙烯酸人工晶状体（IOL）出现混浊，视力显著下降。亲水性丙烯酸IOL混浊主要是由于晶状体材料表面形成褶皱，其次是磷酸钙沉积。钙化混浊可归因于近期事件，二水磷酸二钙（CaHPO₂·H₂O）和磷酸八钙（Ca₈H₂(PO₄)₅·5H₂O）的沉积证明了这一点，这两种都是短暂的磷酸钙相，会水解转化为热力学上最稳定的羟基磷灰石（Ca₁₀(PO₄)₆(OH)₂）。据我们所知，这例亲水性丙烯酸IOL混浊是白内障手术后23年才出现的唯一病例。
