Department of Biotechnology, An Giang University, Vietnam National University, 18 Ung Van Khiem, Long Xuyen City 880000, Vietnam.
Vietnam National University Ho Chi Minh, Thu Duc City, HCM City 71308, Vietnam.
Biomolecules. 2024 Sep 16;14(9):1162. doi: 10.3390/biom14091162.
Microbial exopolysaccharides (EPSs) are receiving growing interest today, owing to their diversity in chemical structure and source, multiple functions, and immense potential applications in many food and non-food industries. Their health-promoting benefits for humans deserve particular attention because of their various biological activities and physiological functions. The aim of this paper is to provide a comprehensive review of microbial EPSs, covering (1) their chemical and biochemical diversity, including composition, biosynthesis, and bacterial sources belonging mainly to lactic acid bacteria (LAB) or probiotics; (2) their technological and analytical aspects, especially their production mode and characterization; (3) their biological and physiological aspects based on their activities and functions; and (4) their current and future uses in medical and pharmaceutical fields, particularly for their prebiotic, anticancer, and immunobiotic properties, as well as their applications in other industrial and agricultural sectors.
微生物胞外多糖(EPSs)因其化学结构和来源的多样性、多种功能以及在许多食品和非食品工业中的巨大潜在应用而受到越来越多的关注。由于其各种生物活性和生理功能,它们对人类的健康促进益处值得特别关注。本文的目的是提供对微生物 EPSs 的全面综述,涵盖(1)它们的化学和生化多样性,包括组成、生物合成以及主要属于乳酸菌(LAB)或益生菌的细菌来源;(2)它们的技术和分析方面,特别是它们的生产模式和特性;(3)基于其活性和功能的生物学和生理学方面;以及(4)它们在医学和制药领域的当前和未来用途,特别是它们作为益生元、抗癌和免疫生物的特性,以及它们在其他工业和农业领域的应用。