Kang Minchae, Seo Suyeon, Lee Hyewon, Han Min-Woo
Department of Mechanical Engineering, Advanced Manufacturing & Soft Robotics Lab, Dongguk University, 30 Pildong-ro 1, Jung-gu, Seoul 04620, Republic of Korea.
Department of Mechanical, Robotics and Energy Engineering, Advanced Manufacturing & Soft Robotics Lab, Dongguk University, 30 Pildong-ro 1, Jung-gu, Seoul 04620, Republic of Korea.
Biomimetics (Basel). 2024 Mar 8;9(3):166. doi: 10.3390/biomimetics9030166.
Knee osteoarthritis (OA), also known as degenerative arthritis, is a disease characterized by irreversible changes in the cartilage and bones comprising the joints, resulting in pain, impaired function, and deformity. Furthermore, independent of natural aging, the rate of change in joint cartilage has increased in recent years, which is mainly attributed to environmental factors. The rising incidence of knee-related disorders emphasizes the importance of analyzing the morphology and kinematics of knee structure. This study introduces a knee measurement system designed to replicate the motions of knee using 3D-printing technology, providing insights into knee mechanics with OA level. The research explores the stages of OA using the Kellgren-Lawrence (KL) grade scale, highlighting the variations in the force applied to the knee bone according to movement. The developed knee-simulation system, utilizing the four-bar-link theory, presents a novel approach to studying OA levels 0 to 4. As OA progresses, the cartilage deteriorates, affecting the movement of OA. The OA-based knee measurement system that incorporates soft tissues and skeletons can assist in developing a personalized diagnostic approach for knee disease. This will also help to enhance surgical effectiveness by facilitating the creation of personalized prosthetic joints for individual patients and offering a customized surgical simulation.
膝关节骨关节炎（OA），也称为退行性关节炎，是一种以构成关节的软骨和骨骼发生不可逆变化为特征的疾病，会导致疼痛、功能受损和畸形。此外，与自然衰老无关，近年来关节软骨的变化速度有所增加，这主要归因于环境因素。膝关节相关疾病发病率的上升凸显了分析膝关节结构形态和运动学的重要性。本研究介绍了一种膝关节测量系统，该系统旨在利用3D打印技术复制膝关节的运动，为骨关节炎水平下的膝关节力学提供见解。该研究使用凯尔格伦-劳伦斯（KL）分级量表探索骨关节炎的阶段，突出了根据运动施加在膝关节骨上的力的变化。所开发的膝关节模拟系统利用四连杆理论，提出了一种研究0至4级骨关节炎的新方法。随着骨关节炎的进展，软骨会恶化，影响骨关节炎的运动。结合软组织和骨骼的基于骨关节炎的膝关节测量系统可以帮助开发针对膝关节疾病的个性化诊断方法。这也将有助于通过为个体患者制作个性化的假体关节并提供定制的手术模拟来提高手术效果。
