为保护婴儿进行的产前母体免疫：推荐疫苗、婴儿免疫及未来研究方向综述
Prenatal Maternal Immunization for Infant Protection: A Review of the Vaccines Recommended, Infant Immunity and Future Research Directions.
作者信息
Quincer Elizabeth M, Cranmer Lisa M, Kamidani Satoshi
机构信息
Immunization Safety Office, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
出版信息
Pathogens. 2024 Feb 23;13(3):200. doi: 10.3390/pathogens13030200.
Abstract
Prenatal maternal immunization is an effective tool to protect mothers and infants from poor health outcomes due to infectious diseases. We provide an overview of the rationale for the use of prenatal vaccines, discuss the immunologic environment of the maternal-fetal interface including the impact of maternal vaccines prenatally and subsequently on the infant's immune response, and review vaccines currently recommended in pregnancy and landscape for the future of maternal vaccination. This review aims to provide an understanding of the recent history and progress made in the field and highlight the importance of continued research and development into new vaccines for pregnant populations.
摘要
产前母体免疫是保护母亲和婴儿免受传染病导致的不良健康后果的有效工具。我们概述了使用产前疫苗的基本原理，讨论了母胎界面的免疫环境，包括产前母体疫苗及其后续对婴儿免疫反应的影响，并回顾了目前孕期推荐的疫苗以及母体疫苗接种的未来前景。本综述旨在增进对该领域近期历史和进展情况的了解，并强调继续研发针对孕妇群体的新疫苗的重要性。
相似文献
1
Prenatal Maternal Immunization for Infant Protection: A Review of the Vaccines Recommended, Infant Immunity and Future Research Directions.为保护婴儿进行的产前母体免疫：推荐疫苗、婴儿免疫及未来研究方向综述
Pathogens. 2024 Feb 23;13(3):200. doi: 10.3390/pathogens13030200.
2
The effect of maternal antibodies on the cellular immune response after infant vaccination: A review.母体抗体对婴儿接种后细胞免疫应答的影响：综述。
Vaccine. 2020 Jan 3;38(1):20-28. doi: 10.1016/j.vaccine.2019.10.025. Epub 2019 Oct 28.
3
Maternal immunization.母体免疫
Clin Infect Dis. 2014 Aug 15;59(4):560-8. doi: 10.1093/cid/ciu327. Epub 2014 May 5.
4
Antenatal immunization.产前免疫
Hum Vaccin Immunother. 2014;10(7):2118-22. doi: 10.4161/hv.29610.
5
Maternal immunization as a strategy to decrease susceptibility to infection in newborn infants.母体免疫接种作为降低新生儿感染易感性的策略。
Curr Opin Infect Dis. 2013 Jun;26(3):248-53. doi: 10.1097/QCO.0b013e3283607a58.
6
Maternal Vaccination as an Essential Component of Life-Course Immunization and Its Contribution to Preventive Neonatology.孕产妇疫苗接种作为生命全程免疫规划的一个基本组成部分及其对预防新生儿学的贡献。
Int J Environ Res Public Health. 2018 Apr 25;15(5):847. doi: 10.3390/ijerph15050847.
7
Maternal immunization.母亲免疫接种。
Birth Defects Res. 2017 Mar 15;109(5):379-386. doi: 10.1002/bdra.23547.
8
Review of maternal immunisation during pregnancy: focus on pertussis and influenza.孕期母体免疫综述：聚焦百日咳和流感
Swiss Med Wkly. 2017 Oct 27;147:w14526. doi: 10.4414/smw.2017.14526. eCollection 2017.
9
Strategies To Boost Maternal Immunization To Achieve Further Gains In Improved Maternal And Newborn Health.加强孕产妇免疫以进一步改善孕产妇和新生儿健康的策略
Health Aff (Millwood). 2016 Feb;35(2):309-16. doi: 10.1377/hlthaff.2015.1090.
10
Immune interference (blunting) in the context of maternal immunization with Tdap-containing vaccines: is it a class effect?含 Tdap 疫苗的母亲免疫中的免疫干扰（钝化）：这是一类效应吗？
Expert Rev Vaccines. 2020 Apr;19(4):341-352. doi: 10.1080/14760584.2020.1749597. Epub 2020 May 7.
引用本文的文献
1
Beyond Passive Immunity: Three Neonatal Influenza Cases Highlighting Impact of Missed Maternal Vaccination.超越被动免疫：三例新生儿流感病例凸显母亲疫苗接种遗漏的影响
Clin Pract. 2025 Jun 30;15(7):124. doi: 10.3390/clinpract15070124.
2
From Womb to Mind: Prenatal Epigenetic Influences on Mental Health Disorders.从子宫到心灵：产前表观遗传学对精神疾病的影响
Int J Mol Sci. 2025 Jun 25;26(13):6096. doi: 10.3390/ijms26136096.
3
Maternal Vaccination and Neonatal Feeding Strategies Among Polish Women.波兰女性的孕产妇疫苗接种与新生儿喂养策略
Vaccines (Basel). 2025 Mar 31;13(4):376. doi: 10.3390/vaccines13040376.
4
Evaluating the Efficacy and Safety of Hepatitis E Vaccination in Reproductive-Age Women: A Systematic Review and Meta-Analysis.评估戊型肝炎疫苗在育龄妇女中的有效性和安全性：一项系统评价和荟萃分析。
Vaccines (Basel). 2025 Jan 9;13(1):53. doi: 10.3390/vaccines13010053.
5
RSM01, a novel respiratory syncytial virus monoclonal antibody: preclinical characterization and results of a first-in-human, randomised clinical trial.RSM01，一种新型呼吸道合胞病毒单克隆抗体：临床前特征及首例人体随机临床试验结果
BMC Infect Dis. 2024 Dec 3;24(1):1378. doi: 10.1186/s12879-024-10120-w.
6
Molecular epidemiology and virulence factors of group B Streptococcus in South Korea according to the invasiveness.根据侵袭性，韩国 B 群链球菌的分子流行病学和毒力因子。
BMC Infect Dis. 2024 Jul 26;24(1):740. doi: 10.1186/s12879-024-09625-1.
本文引用的文献
1
Pregnancy and infant outcomes following SARS-CoV-2 infection in pregnancy during delta variant predominance - Surveillance for Emerging Threats to Pregnant People and Infants.德尔塔变异株流行期间孕妇感染 SARS-CoV-2 后的妊娠和婴儿结局 - 对孕妇和婴儿的新发威胁进行监测。
Am J Obstet Gynecol MFM. 2024 Feb;6(2):101265. doi: 10.1016/j.ajogmf.2023.101265. Epub 2023 Dec 21.
2
Influenza, Updated COVID-19, and Respiratory Syncytial Virus Vaccination Coverage Among Adults - United States, Fall 2023.流感、更新的 COVID-19 和呼吸道合胞病毒疫苗接种覆盖率在成年人中-美国，2023 年秋季。
MMWR Morb Mortal Wkly Rep. 2023 Dec 22;72(51):1377-1382. doi: 10.15585/mmwr.mm7251a4.
3
Maternal Vaccine Effectiveness Against Influenza-Associated Hospitalizations and Emergency Department Visits in Infants.母亲接种疫苗对婴儿因流感相关住院和急诊就诊的有效性。
JAMA Pediatr. 2024 Feb 1;178(2):176-184. doi: 10.1001/jamapediatrics.2023.5639.
4
CDC COVID-19 Vaccine Pregnancy Registry: Design, data collection, response rates, and cohort description.疾病预防控制中心 COVID-19 疫苗妊娠登记处：设计、数据收集、回复率和队列描述。
Vaccine. 2024 Mar 7;42(7):1469-1477. doi: 10.1016/j.vaccine.2023.11.061. Epub 2023 Dec 6.
5
Use of Updated COVID-19 Vaccines 2023-2024 Formula for Persons Aged ≥6 Months: Recommendations of the Advisory Committee on Immunization Practices - United States, September 2023.2023-2024 年更新版 COVID-19 疫苗在≥6 月龄人群中的使用：免疫实践咨询委员会的建议——美国，2023 年 9 月。
MMWR Morb Mortal Wkly Rep. 2023 Oct 20;72(42):1140-1146. doi: 10.15585/mmwr.mm7242e1.
6
Use of the Pfizer Respiratory Syncytial Virus Vaccine During Pregnancy for the Prevention of Respiratory Syncytial Virus-Associated Lower Respiratory Tract Disease in Infants: Recommendations of the Advisory Committee on Immunization Practices - United States, 2023.《妊娠期使用辉瑞呼吸道合胞病毒疫苗预防婴儿呼吸道合胞病毒相关下呼吸道疾病：免疫实践咨询委员会建议-美国，2023 年》。
MMWR Morb Mortal Wkly Rep. 2023 Oct 13;72(41):1115-1122. doi: 10.15585/mmwr.mm7241e1.
7
Influenza, Tdap, and COVID-19 Vaccination Coverage and Hesitancy Among Pregnant Women - United States, April 2023.孕妇的流感、Tdap 和 COVID-19 疫苗接种覆盖率和犹豫情况-美国，2023 年 4 月。
MMWR Morb Mortal Wkly Rep. 2023 Sep 29;72(39):1065-1071. doi: 10.15585/mmwr.mm7239a4.
8
Use of Respiratory Syncytial Virus Vaccines in Older Adults: Recommendations of the Advisory Committee on Immunization Practices - United States, 2023.《老年人使用呼吸道合胞病毒疫苗：免疫实践咨询委员会的建议——美国，2023 年》。
MMWR Morb Mortal Wkly Rep. 2023 Jul 21;72(29):793-801. doi: 10.15585/mmwr.mm7229a4.
9
Potential for Maternally Administered Vaccine for Infant Group B Streptococcus.母体疫苗预防婴儿 B 群链球菌的潜力。
N Engl J Med. 2023 Jul 20;389(3):215-227. doi: 10.1056/NEJMoa2116045.
10
COVID-19 Booster Vaccination in Early Pregnancy and Surveillance for Spontaneous Abortion.COVID-19 加强针在早孕中的接种和自发性流产的监测。
JAMA Netw Open. 2023 May 1;6(5):e2314350. doi: 10.1001/jamanetworkopen.2023.14350.
Zotero 插件