Division of Neonatology, Department of Paediatrics, University Maternity Hospital Limerick (UMHL), Limerick V94 C566, Ireland.
MSD Ireland Ltd., South County Business Park, Leopardstown, Dublin D18 X5K7, Ireland.
Int J Environ Res Public Health. 2018 Apr 25;15(5):847. doi: 10.3390/ijerph15050847.
Maternal immunisation schedules are increasingly coming under the spotlight as part of the development of lifetime immunisation programmes for the role that they play in improving maternal, foetal, and neonatal health. Maternally-acquired antibodies are critical in protecting infants during the first months of their lives. Maternal immunisation was previously overlooked owing to concerns regarding vaccinations in this untested and high-risk population but is now acknowledged for its potential impact on the outcomes in many domains of foetal and neonatal health, aside from its maternal benefits. This article highlights the role that maternal immunisation may play in reducing infections in preterm and term infants. It explores the barriers to antenatal vaccinations and the optimisation of the immunisation uptake. This review also probes the part that maternal immunisation may hold in the reduction of perinatal antimicrobial resistance and the prevention of non-infectious diseases. Both healthcare providers and expectant mothers should continue to be educated on the importance and safety of the appropriate immunizations during pregnancy. Maternal vaccination merits its deserved priority in a life-course immunization approach and it is perhaps the only immunization whereby two generations benefit directly from a single input. We outline the current recommendations for antenatal vaccinations and highlight the potential advances in the field contributing to “”.
作为制定终身免疫计划的一部分，母体免疫接种计划越来越受到关注，因为它们在改善母婴、胎儿和新生儿健康方面发挥着重要作用。母体获得的抗体对于保护婴儿在生命的头几个月至关重要。由于对这一未经测试和高风险人群的疫苗接种存在担忧，母体免疫接种以前被忽视，但现在由于其对胎儿和新生儿健康许多领域的结果的潜在影响而得到认可，除了其对母体的益处之外。本文强调了母体免疫接种在减少早产儿和足月婴儿感染方面可能发挥的作用。它探讨了产前疫苗接种的障碍和免疫接种率的优化。本综述还探讨了母体免疫接种在减少围产期抗菌药物耐药性和预防非传染性疾病方面的作用。医疗保健提供者和孕妇都应继续接受有关怀孕期间适当免疫接种的重要性和安全性的教育。母体疫苗接种在终身免疫接种方法中应得到应有的重视，也许它是唯一一种通过单次投入就能使两代人直接受益的免疫接种。我们概述了产前疫苗接种的当前建议，并强调了该领域的潜在进展，这有助于“”。
