Institute for Plant Protection in Field Crops and Grassland, Julius Kühn Institute (JKI)-Federal Research Centre for Cultivated Plants, 38104 Braunschweig, Germany.
Molecular Phytopathology and Mycotoxin Research, University of Göttingen, 37077 Göttingen, Germany.
Toxins (Basel). 2024 Mar 2;16(3):131. doi: 10.3390/toxins16030131.
RNA viruses of the genera , , , and were found in a single isolate of . The genomes of the mitovirus, sclerotimonavirus, and partitivirus were assigned to previously described viruses, whereas the ambivirus genome putatively represents a new species, named 1 (FgAV1). To investigate the effect of mycoviruses on the fungal phenotype, the spontaneous loss of mycoviruses during meiosis and the transmission of mycoviruses into a new strain via anastomosis were used to obtain isogenic strains both with and without mycoviruses. Notable effects observed in mycovirus-harboring strains were (i) the suppression of the synthesis of trichothecene mycotoxins and their precursor trichodiene, (ii) the suppression of the synthesis of the defense compound aurofusarin, (iii) the stimulation of the emission of 2-methyl-1-butanol and 3-methyl-1-butanol, and (iv) the increased attractiveness of fungal mycelia for fungivorous collembolans. The increased attractiveness of mycovirus-infected filamentous fungi to animal predators opens new perspectives on the ecological implications of the infection of fungi with viruses.
属、属、属和属的 RNA 病毒在单个分离物中被发现。其中，拟病毒、潜隐病毒和部分病毒的基因组被分配到先前描述的病毒中，而 ambivirus 基因组推测代表了一种新的病毒，命名为 1（FgAV1）。为了研究真菌病毒对真菌表型的影响，利用减数分裂过程中真菌病毒的自发丢失以及通过吻合将真菌病毒传播到新菌株的方式，获得了具有和不具有真菌病毒的同基因菌株。在携带真菌病毒的菌株中观察到了显著的效应，包括(i) 抑制了杂色曲霉素真菌毒素及其前体表二烯的合成，(ii) 抑制了防御化合物金核菌素的合成，(iii) 刺激了 2-甲基-1-丁醇和 3-甲基-1-丁醇的排放，以及 (iv) 真菌菌丝对食真菌跳虫的吸引力增加。感染病毒的真菌对动物捕食者的吸引力增加，为真菌病毒感染的生态影响开辟了新的视角。
