State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China.
Front Cell Infect Microbiol. 2019 Jul 18;9:257. doi: 10.3389/fcimb.2019.00257. eCollection 2019.
is an important genus of plant pathogenic fungi, and is widely distributed in soil and associated with plants worldwide. The diversity of mycoviruses in is increasing continuously due to the development and extensive use of state-of-the-art RNA deep sequencing techniques. To date, fully-sequenced mycoviruses have been reported in 13 species: , and . Most mycoviruses establish latent infections, but some mycoviruses such as Fusarium graminearum virus 1 (FgV1), Fusarium graminearum virus-ch9 (FgV-ch9), Fusarium graminearum hypovirus 2 (FgHV2), and f. sp. dianthi mycovirus 1 (FodV1) cause hypovirulence. Rapid advances in various omics technologies used to elucidate genes or biological processes can facilitate an improved understanding of mycovirus-host interactions. The review aims to illuminate the recent advances in studies of mycoviruses in , including those related to diversity, molecular mechanisms of virus-host interaction. We also discuss the induction and suppression of RNA silencing including the role of RNAi components as an antiviral defense response.
是植物病原真菌中的一个重要属，广泛分布于土壤中，并与世界各地的植物有关。由于先进的 RNA 深度测序技术的发展和广泛应用， 的真菌病毒多样性不断增加。迄今为止，已在 13 个 种中报道了完全测序的真菌病毒： 、 、 。大多数 真菌病毒建立潜伏感染，但一些真菌病毒，如禾谷镰刀菌病毒 1（FgV1）、禾谷镰刀菌病毒-ch9（FgV-ch9）、禾谷镰刀菌类病毒 2（FgHV2）和 f. sp. dianthi 真菌病毒 1（FodV1），可导致弱毒。用于阐明基因或生物学过程的各种组学技术的快速发展，可以促进对真菌病毒-宿主相互作用的更好理解。该综述旨在阐明 在真菌病毒研究方面的最新进展，包括与多样性、病毒-宿主相互作用的分子机制相关的研究。我们还讨论了 RNA 沉默的诱导和抑制，包括 RNAi 成分作为抗病毒防御反应的作用。
