Child Health Evaluative Sciences, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, 686 Bay St, Toronto, ON, M5G 0A4, Canada.
Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Eur J Pediatr. 2024 Jun;183(6):2521-2526. doi: 10.1007/s00431-024-05499-2. Epub 2024 Mar 27.
Research suggests that vaping raises oxidative stress levels and has been implicated in poor mental health. The objective of this study is to assess cross-sectional associations between quality of life (QOL) indicators and e-cigarette (EC) use in young Canadian adults. We used data from the 2016-2017 Canadian Health Measures Survey. We compared physical activity (daily steps), physiological measurements (high-density lipoprotein for cholesterol level), self-perceived life stress, mental health, and QOL between ever-use EC users and non-users. Multivariable binary or ordinal logistic regressions were used to calculate odds ratios (OR) with 95% confidence intervals (CI). Analyses included 905 participants (15-30 years) with 115 (12.7%) reporting EC use and 790 non-users. After adjusting for confounders, compared to non-users, EC users had significantly higher odds of being physically active (OR = 2.19, 95%CI: 1.14-4.20) but also with self-reported extreme life stress (OR = 2.68, 95%CI: 1.45-4.92). Albeit statistically non-significant, EC users also had higher odds of poorer QOL (OR = 1.12, 95%CI: 0.64-1.95). No statistically significant interactions between EC use, cigarette smoking, cannabis consumption and health outcomes were observed.
Our study found that EC use was independently and significantly associated with increased odds of life stress and an indication of poorer QOL. Ongoing surveillance on young EC users is important to measure the long-term impact of vaping on their physical, mental health and quality of life to target for interventions.
• E-cigarette use has been associated with high-risk behaviours and adverse mental health outcomes, such as depression and anxiety.
• E-cigarette users had significantly higher odds of being physically active and higher amounts of life stress.
评估生活质量（QOL）指标与加拿大年轻成年人使用电子烟（EC）之间的横断面关联。
我们使用了 2016-2017 年加拿大健康测量调查的数据。我们比较了电子烟使用者和非使用者的身体活动（每日步数）、生理测量（高密度脂蛋白胆固醇水平）、自我感知生活压力、心理健康和 QOL。使用多变量二项或有序逻辑回归计算比值比（OR）和 95%置信区间（CI）。分析包括 905 名（15-30 岁）参与者，其中 115 名（12.7%）报告使用 EC，790 名非使用者。在调整混杂因素后，与非使用者相比，EC 使用者体力活动的可能性显著更高（OR=2.19，95%CI：1.14-4.20），但自我报告的极端生活压力的可能性也更高（OR=2.68，95%CI：1.45-4.92）。尽管统计学上无显著差异，但 EC 使用者的 QOL 更差的可能性也更高（OR=1.12，95%CI：0.64-1.95）。未观察到 EC 使用、吸烟、大麻使用与健康结果之间存在统计学显著交互作用。
我们的研究发现，EC 使用与生活压力增加和 QOL 下降的可能性独立且显著相关。对年轻 EC 用户进行持续监测对于衡量 vaping 对他们的身心健康和生活质量的长期影响非常重要，以便进行干预。
