Department of Ophthalmology, New Civil Hospital, Strasbourg University Hospital, FMTS, University of Strasbourg, Strasbourg, France.
INSERM, French National Institute of Health and Medical Research, UMR 1260, Regenerative Nano Medicine, University of Strasbourg, Strasbourg, France.
Int Ophthalmol. 2024 Mar 27;44(1):162. doi: 10.1007/s10792-024-02998-x.
We aimed to identify ocular comorbidities and reasons of blindness in monocular patients and to compare visual outcomes of cataract surgery between monocular and binocular patients.
A single-center case-control study was conducted between November 2011 and May 2019 to compare consecutive series of patients needing cataract surgery in Strasbourg University Hospitals, France. Cases were patients with permanent monocular vision loss. Controls were binocularly sighted patients. All patients underwent cataract surgery using phacoemulsification technique. Chart analysis included demographic data, medical history, and surgical determinants data. Student's t tests and Fisher's exact tests were the main methods used for statistical analysis.
Each group included 80 patients. The mean age at the time of surgery was significantly higher in monocular than binocular patients (77 vs. 71 years, p < 0.001). Thirty-two monocular patients (40%) had ocular comorbidities, compared to only 19 (23%) in the control group (p < 0.05). The leading cause of monocular status was amblyopia caused by strabismus (22 patients, 27.5%). Age-related macular degeneration, open-angle glaucoma, and diabetic retinopathy were the three main ocular comorbidities that were observed in the monocular group. Monocular patients had significantly lower visual acuity than the control group (p < 0.01) before and after cataract surgery. Conversely, improvement in visual acuity after surgery was not statistically different between groups (p = 0.054). There was no statistically significant difference in the rate of surgical complications between groups (p = 0.622).
This study illustrates that cataract surgery in monocular patients is not more complicated than in binocular patients, but that it is significantly delayed.
我们旨在确定单眼患者的眼部合并症和失明原因，并比较单眼和双眼患者白内障手术后的视力结果。
这是一项在 2011 年 11 月至 2019 年 5 月期间在法国斯特拉斯堡大学附属医院进行的单中心病例对照研究，比较了连续系列需要白内障手术的患者。病例为永久性单眼视力丧失的患者。对照组为双眼视力正常的患者。所有患者均接受超声乳化白内障吸除术。图表分析包括人口统计学数据、病史和手术决定因素数据。学生 t 检验和 Fisher 确切检验是主要的统计分析方法。
每组各有 80 名患者。单眼组手术时的平均年龄明显高于双眼组（77 岁比 71 岁，p<0.001）。32 名单眼患者（40%）有眼部合并症，而对照组只有 19 名（23%）（p<0.05）。单眼状态的主要原因是斜视引起的弱视（22 例，27.5%）。年龄相关性黄斑变性、开角型青光眼和糖尿病性视网膜病变是单眼组观察到的三种主要眼部合并症。单眼患者的视力明显低于对照组（p<0.01），无论术前还是术后。然而，手术后视力的改善在两组之间没有统计学上的差异（p=0.054）。两组之间手术并发症的发生率没有统计学上的差异（p=0.622）。
本研究表明，单眼患者的白内障手术并不比双眼患者更复杂，但手术明显延迟。
