Klotzek Adam, Jemni Monem, Groves Shad James, Carrick Frederick Robert
Department of Neurology, Carrick Institute, Cape Canaveral, FL 32920, USA.
Centre for Mental Health Research in Association, University of Cambridge, Cambridge CB2 1TN, UK.
Brain Sci. 2024 Mar 20;14(3):292. doi: 10.3390/brainsci14030292.
Quantifying saccadic eye movements can assist in identifying dysfunctional brain networks in both healthy and diseased people. Infrared Oculography is a simple and non-invasive approach to capturing and quantifying saccades, providing information that might aid in diagnosis and outcome assessments. The effect of spinal manipulation on quantified saccadic performance parameters has not been fully studied despite known post-manipulative effects on the brain and brainstem regions controlling them. This case study investigates spinal manipulation's immediate and long-term effects on saccadic eye movements by quantifying the saccades of a male patient diagnosed with post-concussion syndrome. The patient performed horizontal saccades that were quantified before and immediately following cervical spinal manipulation both at the case study's start and following a 2-week interim, during which the subject received six manipulative treatments. Immediate and long-term post-manipulative effects were observed, and the results revealed various post-manipulative effects across all quantified parameters in addition to between right and leftward saccades. The immediate post-manipulative effect was greatest at the case study's onset, while the long-term right and leftward saccadic symmetry were most affected. The observations in this case study demonstrate that cervical spinal manipulation influences saccadic eye movements, providing new insights into its central neurological effects and therapeutic applications beyond its most commonly known use in pain management. More importantly, it encourages scientists to undertake further clinical investigations on wider scales.
量化眼球跳动有助于识别健康人群和患病者大脑网络的功能障碍。红外眼动描记术是一种简单且无创的捕捉和量化眼球跳动的方法，可提供有助于诊断和结果评估的信息。尽管已知脊柱推拿对控制眼球跳动的大脑和脑干区域有手法后效应，但脊柱推拿对量化眼球跳动性能参数的影响尚未得到充分研究。本案例研究通过量化一名被诊断为脑震荡后综合征的男性患者的眼球跳动，来调查脊柱推拿对眼球跳动的即时和长期影响。在案例研究开始时以及经过2周的中期阶段（在此期间该受试者接受了6次推拿治疗）后，患者进行了水平眼球跳动，并在颈椎推拿前后立即对其进行了量化。观察到了手法后的即时和长期效应，结果显示除了左右眼球跳动之间，所有量化参数在手法后都有各种效应。手法后的即时效应在案例研究开始时最大，而长期的左右眼球跳动对称性受影响最大。本案例研究中的观察结果表明，颈椎推拿会影响眼球跳动，为其在疼痛管理之外的中枢神经效应和治疗应用提供了新的见解。更重要的是，它鼓励科学家进行更大规模的进一步临床研究。
