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从益生菌特性到组学技术的理解:综述

Understanding from Probiotic Properties to Omics Technology: A Review.

作者信息

Yang Yong, Song Xin, Wang Guangqiang, Xia Yongjun, Xiong Zhiqiang, Ai Lianzhong

机构信息

Shanghai Engineering Research Center of Food Microbiology, University of Shanghai for Science and Technology, Shanghai 200093, China.

出版信息

Foods. 2024 Mar 15;13(6):895. doi: 10.3390/foods13060895.

Abstract

(basonym: , ) is a type of lactic acid bacteria (LAB) commonly found in the oropharyngeal-gastrointestinal tract (OGT). It has gained significant attention due to its probiotic and functional properties as well as its various health-promoting roles. strains exhibit strong resistance and adhesion in the OGT along with outstanding antioxidant and antimicrobial properties. Additionally, numerous strains have the ability to produce bacteriocins with antagonistic activity. These probiotic characteristics of indicate its remarkable potential in promoting favorable effects on human health. It has also been observed that has a positive effect on the composition of intestinal microbiota, thereby improving the metabolic profiling of intestinal microbiota, promoting a healthy and balanced internal environment. In recent years, multi-omics technologies such as genomics, transcriptomics, proteomics and metabolomics have been employed to gain a deeper understanding of the roles and mechanisms of associated with its functional properties. This review aims to provide an overview of the probiotic characteristics of , containing its specific interactions with the host microflora, as well as insights from omics studies.

摘要

(基原异名: , )是一种常见于口咽-胃肠道(OGT)的乳酸菌(LAB)。由于其益生菌和功能特性以及各种促进健康的作用,它受到了广泛关注。 菌株在OGT中表现出强大的抗性和黏附性,同时具有出色的抗氧化和抗菌特性。此外,许多 菌株能够产生具有拮抗活性的细菌素。 的这些益生菌特性表明其在促进对人类健康的有益作用方面具有显著潜力。还观察到 对肠道微生物群的组成有积极影响,从而改善肠道微生物群的代谢谱,促进健康和平衡的内部环境。近年来,基因组学、转录组学、蛋白质组学和代谢组学等多组学技术已被用于更深入地了解 与其功能特性相关的作用和机制。本综述旨在概述 的益生菌特性,包括其与宿主微生物群的特定相互作用,以及组学研究的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/075b/10969406/f5c301f64cde/foods-13-00895-g001.jpg

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