Ibach Marius, Winter Axel, Seika Philippa, Ritschl Paul, Berndt Nadja, Dobrindt Eva, Raakow Jonas, Pratschke Johann, Denecke Christian, Maurer Max Magnus
Chirurgische Klinik, Campus Charité Mitte/Campus Virchow-Klinikum, Charité Universitätsmedizin Berlin, 13353 Berlin, Germany.
Berlin Institute of Health at Charité-Universitätsmedizin Berlin, BIH Biomedical Innovation Academy, BIH Charité Clinician Scientist Program, Charitéplatz 1, 10117 Berlin, Germany.
J Clin Med. 2024 Mar 8;13(6):1560. doi: 10.3390/jcm13061560.
Disruptions to surgical care for cancer patients during the COVID-19 pandemic remain an ongoing debate. This study assesses the effects of the COVID-19 pandemic on perioperative outcomes in a continuous series of surgically treated esophageal and gastric carcinoma patients at a large university hospital in Europe over 48 months. We conducted a retrospective single-center cohort study at a tertiary referral center. All patients who underwent oncologic esophageal or gastric resection between March 2018 and February 2022 were included in the analysis. The sample was split into a 24 months COVID-19 and an equivalent pre-COVID-19 control period. Outcome variables included caseload, in-hospital mortality, morbidity, treatment course, and disease stage at presentation. Surgeons performed 287 operations, with around two-thirds (62%) of the cohort undergoing esophagectomy and one-third (38%) gastrectomy. The in-hospital mortality was 1% for the COVID-19 and the control periods. Patients did not present at a later disease stage nor did they wait longer for treatment. There was no decrease in caseload, and patients did not suffer from more perioperative complications during COVID-19. Esophageal and gastric carcinoma patients received safe and timely surgical care during the pandemic. Future pandemic protocols may streamline oncologic care towards tertiary referral centers.
在新冠疫情期间,癌症患者手术治疗的中断仍是一个持续争论的话题。本研究评估了新冠疫情对欧洲一家大型大学医院连续48个月接受手术治疗的食管癌和胃癌患者围手术期结局的影响。我们在一家三级转诊中心进行了一项回顾性单中心队列研究。分析纳入了2018年3月至2022年2月期间接受肿瘤性食管或胃切除术的所有患者。样本被分为24个月的新冠疫情期和与之对应的新冠疫情前对照期。结局变量包括病例数、住院死亡率、发病率、治疗过程以及就诊时的疾病分期。外科医生共进行了287例手术,队列中约三分之二(62%)的患者接受了食管切除术,三分之一(38%)的患者接受了胃切除术。新冠疫情期和对照期的住院死亡率均为1%。患者就诊时疾病分期没有延迟,等待治疗的时间也没有延长。病例数没有减少,患者在新冠疫情期间也没有出现更多的围手术期并发症。食管癌和胃癌患者在疫情期间接受了安全及时的手术治疗。未来的疫情应对方案可能会使肿瘤治疗流程更趋向于三级转诊中心。