Shu Chien-Gene Lay Department of Bioengineering, University of California San Diego, San Diego, CA 92093-0021, USA.
UC San Diego Health Department of Biomedical Informatics, University of California San Diego, San Diego, CA 92093-0021, USA.
Sensors (Basel). 2024 Mar 12;24(6):1818. doi: 10.3390/s24061818.
Commercially available wearable devices (wearables) show promise for continuous physiological monitoring. Previous works have demonstrated that wearables can be used to detect the onset of acute infectious diseases, particularly those characterized by fever. We aimed to evaluate whether these devices could be used for the more general task of syndromic surveillance. We obtained wearable device data (Oura Ring) from 63,153 participants. We constructed a dataset using participants' wearable device data and participants' responses to daily online questionnaires. We included days from the participants if they (1) completed the questionnaire, (2) reported not experiencing fever and reported a self-collected body temperature below 38 °C (negative class), or reported experiencing fever and reported a self-collected body temperature at or above 38 °C (positive class), and (3) wore the wearable device the nights before and after that day. We used wearable device data (i.e., skin temperature, heart rate, and sleep) from the nights before and after participants' fever day to train a tree-based classifier to detect self-reported fevers. We evaluated the performance of our model using a five-fold cross-validation scheme. Sixteen thousand, seven hundred, and ninety-four participants provided at least one valid ground truth day; there were a total of 724 fever days (positive class examples) from 463 participants and 342,430 non-fever days (negative class examples) from 16,687 participants. Our model exhibited an area under the receiver operating characteristic curve (AUROC) of 0.85 and an average precision (AP) of 0.25. At a sensitivity of 0.50, our calibrated model had a false positive rate of 0.8%. Our results suggest that it might be possible to leverage data from these devices at a public health level for live fever surveillance. Implementing these models could increase our ability to detect disease prevalence and spread in real-time during infectious disease outbreaks.
市售可穿戴设备(wearables)在连续生理监测方面具有广阔的应用前景。先前的研究表明,可穿戴设备可用于检测急性传染病的发作,尤其是那些以发热为特征的传染病。我们旨在评估这些设备是否可用于更广泛的症状监测任务。我们从 63153 名参与者中获得了可穿戴设备数据(Oura Ring)。我们使用参与者的可穿戴设备数据和他们对每日在线问卷的反馈构建了一个数据集。如果参与者满足以下条件,我们将其包含在数据集中:(1)完成问卷;(2)报告未出现发热且报告自我采集的体温低于 38°C(阴性类别),或报告出现发热且报告自我采集的体温为 38°C 或更高(阳性类别);(3)在该日前后的晚上佩戴可穿戴设备。我们使用参与者发热日前后晚上的可穿戴设备数据(即皮肤温度、心率和睡眠)来训练基于树的分类器以检测自我报告的发热。我们使用五重交叉验证方案评估了我们模型的性能。16794 名参与者至少提供了一天有效的真实数据;463 名参与者中有 724 天(阳性类别示例)出现发热,16687 名参与者中有 342430 天(阴性类别示例)未出现发热。我们的模型的接收者操作特征曲线(AUROC)下面积为 0.85,平均精度(AP)为 0.25。在灵敏度为 0.50 时,我们校准后的模型的假阳性率为 0.8%。我们的研究结果表明,在公共卫生层面上,利用这些设备的数据进行实时发热监测是可行的。实施这些模型可以提高我们在传染病爆发期间实时检测疾病流行和传播的能力。