Chen Zhuo, Cao Bingyan, Liu Lu, Tang Xudong, Xu Hao
Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Jining Hospital of Traditional Chinese Medicine, Jining, China.
Front Nutr. 2024 Mar 13;11:1304127. doi: 10.3389/fnut.2024.1304127. eCollection 2024.
Few studies are about the relationship between anemia and obesity, and previous studies have only paid attention to BMI.
We first included body fat percentage (BF%) as an assessment indicator and divided it into quartiles, grouped participants into obesity and non-obesity used data from NHANES database. After adjustment for age, gender, ethnicity, education and family income, the level of soluble transferrin receptor (sTfR), and incidence of elevated CRP or HsCRP were progressively higher with increased BF%, whereas mean cell volume (MCV), natural logarithm (Ln) serum ferritin (SF), and Ln SF/sTfR were progressively reduced. Although a higher prevalence of anemia and lower hemoglobin was observed with increased BF%, but there was no statistical difference. Women in the highest BF% group demonstrated a significantly higher risk of iron deficiency compared to those in the lowest BF% group.
BF% should be given more attention, and women with high BF% should pay attention to iron deficiency.
关于贫血与肥胖之间关系的研究较少，且以往研究仅关注体重指数（BMI）。
我们首先将体脂百分比（BF%）纳入评估指标并将其分为四分位数，利用美国国家健康与营养检查调查（NHANES）数据库的数据将参与者分为肥胖组和非肥胖组。在对年龄、性别、种族、教育程度和家庭收入、可溶性转铁蛋白受体（sTfR）水平进行校正后，随着BF%的增加，C反应蛋白（CRP）或超敏C反应蛋白（HsCRP）升高的发生率逐渐升高，而平均红细胞体积（MCV）、血清铁蛋白（SF）的自然对数（Ln）以及Ln SF/sTfR则逐渐降低。尽管随着BF%的增加观察到贫血患病率较高且血红蛋白水平较低，但无统计学差异。与BF%最低组的女性相比，BF%最高组的女性缺铁风险显著更高。
应更加关注BF%，BF%高的女性应注意缺铁问题。
