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新兴细胞外囊泡技术在炎症性疾病治疗中的应用。

Applications of emerging extracellular vesicles technologies in the treatment of inflammatory diseases.

机构信息

Department of Urology, Lanxi People's Hospital, Jinhua, Zhejiang, China.

The First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.

出版信息

Front Immunol. 2024 Mar 13;15:1364401. doi: 10.3389/fimmu.2024.1364401. eCollection 2024.

DOI:10.3389/fimmu.2024.1364401
PMID:38545101
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10965547/
Abstract

The emerging extracellular vesicles technologies is an advanced therapeutic approach showing promising potential for addressing inflammatory diseases. These techniques have been proven to have positive effects on immune modulation and anti-inflammatory responses. With these advancements, a comprehensive review and update on the role of extracellular vesicles in inflammatory diseases have become timely. This review aims to summarize the research progress of extracellular vesicle technologies such as plant-derived extracellular vesicles, milk-derived extracellular vesicles, mesenchymal stem cell-derived extracellular vesicles, macrophage-derived extracellular vesicles, etc., in the treatment of inflammatory diseases. It elucidates their potential significance in regulating inflammation, promoting tissue repair, and treating diseases. The goal is to provide insights for future research in this field, fostering the application and development of extracellular vesicle technology in the treatment of inflammatory diseases.

摘要

新兴的细胞外囊泡技术是一种先进的治疗方法,在治疗炎症性疾病方面显示出巨大的潜力。这些技术已被证明对免疫调节和抗炎反应有积极影响。随着这些进展,对细胞外囊泡在炎症性疾病中的作用进行全面的综述和更新变得非常及时。本综述旨在总结植物来源的细胞外囊泡、乳源细胞外囊泡、间充质干细胞来源的细胞外囊泡、巨噬细胞来源的细胞外囊泡等细胞外囊泡技术在治疗炎症性疾病方面的研究进展。阐明了它们在调节炎症、促进组织修复和治疗疾病方面的潜在意义。目的是为该领域的未来研究提供思路,促进细胞外囊泡技术在炎症性疾病治疗中的应用和发展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e07/10965547/0cffcc00a0f3/fimmu-15-1364401-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e07/10965547/a86c2bfa37a3/fimmu-15-1364401-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e07/10965547/0cffcc00a0f3/fimmu-15-1364401-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e07/10965547/a86c2bfa37a3/fimmu-15-1364401-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e07/10965547/0cffcc00a0f3/fimmu-15-1364401-g002.jpg

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