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饮食模式对阻塞性睡眠呼吸暂停患者的影响评估

Assessment of Impact of Dietary Patterns on Obstructive Sleep Apnea Patients.

作者信息

Gunes Fatma Esra, Agan Kadriye, Aktac Sule, Karadeniz Derya, Sunter Gulin, Vural Ezgi, Benbir-Senel Gulcin

机构信息

Department of Nutrition and Dietetics, Faculty of Health Sciences, Marmara University, Istanbul, Turkey.

Department of Neurology, School of Medicine, Marmara University, Istanbul, Turkey.

出版信息

Sleep Sci. 2024 Mar 26;17(1):e82-e89. doi: 10.1055/s-0043-1776745. eCollection 2024 Mar.

DOI:10.1055/s-0043-1776745
PMID:38545237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10965288/
Abstract

Obstructive sleep apnea syndrome (OSAS) is characterized by episodic cessations of breathing due to upper airway obstruction during sleep, which may cause disturbances in dietary patterns resulting from appetite-related hormonal changes. The aim of the present study was to investigate the relationship between OSAS and nutritional and dietary patterns.  A total of 20 female and 53 male OSAS patients aged > 30 years were enrolled. Demographic data, as well as data on smoking and alcohol habits, were noted, anthropometric measures were made, and a questionnaire regarding chronic diseases including OSAS and four questionnaires on recent food intake frequency and content of nutrition were filled out. The content of nutrition was noted under seven categories: meat, legumes, milk and dairy products, fruits and vegetables, bread and cereals, fat and carbohydrates, and beverages.  The severity of OSAS (assessed by the apnea-hypopnea index. AHI) was positively correlated with the body mass index (BMI), the circumferences of the waist, chest, and buttocks, and, in males, with the circumference of the neck as well. There was no correlation between the AHI and nutritional habits in terms of the frequency of meals or snacks, the scores on the Snoring, Tiredness, Observed Apnea, and High Blood Pressure-Body Mass Index, Age, Neck Circumference, and Gender (STOP-BANG) Questionnaire and the corresponding macro- and micronutrients. Worsening apnea scores led to increased intake of macronutrients of carbohydrate and protein and micronutrients of niacin and pyridoxine (  < 0.05), and decreased intake of fat (  < 0.05).  The present study demonstrated an association between OSAS severity and recent food intake, manifested in increased intake of carbohydrates, niacin, and pyridoxine, and decreased fat intake.

摘要

阻塞性睡眠呼吸暂停综合征(OSAS)的特征是睡眠期间因上呼吸道阻塞而出现呼吸间歇性停止,这可能会因食欲相关的激素变化导致饮食模式紊乱。本研究的目的是调查OSAS与营养和饮食模式之间的关系。

共纳入了20名年龄大于30岁的女性和53名男性OSAS患者。记录了人口统计学数据以及吸烟和饮酒习惯数据,进行了人体测量,并填写了一份关于包括OSAS在内的慢性病问卷以及四份关于近期食物摄入频率和营养成分的问卷。营养成分按七类记录:肉类、豆类、牛奶及奶制品、水果和蔬菜、面包和谷物、脂肪和碳水化合物以及饮料。

OSAS的严重程度(通过呼吸暂停低通气指数,即AHI评估)与体重指数(BMI)、腰围、胸围和臀围呈正相关,在男性中还与颈围呈正相关。在进餐或吃零食的频率、打鼾、疲劳、观察到的呼吸暂停以及高血压 - 体重指数、年龄、颈围和性别(STOP - BANG)问卷得分以及相应的常量和微量营养素方面,AHI与营养习惯之间没有相关性。呼吸暂停评分恶化导致碳水化合物和蛋白质等常量营养素以及烟酸和吡哆醇等微量营养素的摄入量增加(P < 0.05),脂肪摄入量减少(P < 0.05)。

本研究表明OSAS严重程度与近期食物摄入之间存在关联,表现为碳水化合物、烟酸和吡哆醇摄入量增加,脂肪摄入量减少。