2nd Department of Ophthalmology, Aristotle University of Thessaloniki, Papageorgiou General Hospital, Thessaloniki, Greece,
Department of Business Administration, University of Macedonia, Thessaloniki, Greece.
Ophthalmic Res. 2021;64(1):50-54. doi: 10.1159/000508954. Epub 2020 May 26.
Cataract is the most common reversible cause of blindness worldwide, and the associated vision impairment has been associated with an adverse impact on health-related quality of life and mental health in particular. However, findings from studies on the mental health improvement of patients after cataract surgery remain inconclusive. The objective of this study is to ascertain whether the outcome on best-corrected visual acuity (BCVA) following cataract surgery is associated with depressive symptomatology.
This is an observational prospective study of a cohort of 150 consecutive patients who underwent phacoemulsification surgery and who were evaluated for changes in depressive symptomatology with Beck's Depression Inventory-II (BDI-II).
The difference in BDI-II scores pre- and postoperatively correlated with the difference in BCVA pre- and postoperatively (p < 0.001). A paired-samples t test revealed a statistically significant difference in the preoperative and postoperative BDI-II scores (p < 0.001). A related-samples Wilcoxon signed-rank test revealed a statistically significant improvement of depression status among the patients (p = 0.004). A stepwise regression analysis concluded that the only statistically significant predictor in assessing the difference in total BDI-II score before and after the operation was the respective difference in visual acuity.
DISCUSSION/CONCLUSION: The success of phacoemulsification surgery for cataract as evaluated with the change in BCVA is related to the rate of improvement in depressive symptomatology.
白内障是全球最常见的可逆转致盲原因，其相关视力损害尤其与健康相关生活质量和心理健康的不良影响相关。然而，关于白内障手术后患者心理健康改善的研究结果仍不一致。本研究旨在确定白内障手术后最佳矫正视力（BCVA）的结果是否与抑郁症状相关。
这是一项对 150 例连续接受超声乳化白内障吸除术的患者进行的前瞻性观察性研究，采用贝克抑郁自评量表（BDI-II）评估患者的抑郁症状变化。
术前和术后 BDI-II 评分的差异与术前和术后 BCVA 的差异相关（p < 0.001）。配对样本 t 检验显示术前和术后 BDI-II 评分有统计学显著差异（p < 0.001）。相关样本 Wilcoxon 符号秩检验显示患者的抑郁状态有统计学显著改善（p = 0.004）。逐步回归分析得出结论，评估手术前后总 BDI-II 评分差异的唯一统计学显著预测因子是视力的相应差异。
讨论/结论：白内障超声乳化吸除术的成功，以 BCVA 的变化来评估，与抑郁症状改善的速度有关。
