迈阿特（MYAH）和 Lenstar 重复性和一致性的研究。

Repeatability and agreement of the MYAH and Lenstar.

机构信息

University of Houston College of Optometry, Houston, Texas.

出版信息

Optom Vis Sci. 2024 Mar 1;101(3):157-163. doi: 10.1097/OPX.0000000000002113.

DOI:10.1097/OPX.0000000000002113

PMID:38546757

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10987055/

Abstract

SIGNIFICANCE

Validation of new biometry instruments against the gold standard and establishing repeatability are important before being utilized for clinical and research applications.

PURPOSE

This study aimed to investigate intersession repeatability of the MYAH optical biometer and corneal topographer and examine agreement with the Lenstar LS900 optical biometer in healthy young adults.

METHODS

Forty participants (mean age, 25.2 ± 3.1 years) presented for two visits, 2 to 4 days apart. At each visit, measurements for right eyes were collected with the MYAH and Lenstar LS 900 and included axial length, corneal power, white-to-white distance, and pupil diameter. Bland-Altman analysis was used to assess the intrasession agreement between the MYAH and Lenstar for each parameter and intersession repeatability for the two devices. For each device, coefficient of variation and intraclass correlation coefficient were calculated, and paired t tests between visits were performed to assess intersession repeatability.

RESULTS

Good agreement (mean difference [95% limits of agreement]) between the MYAH and Lenstar was found for axial length (-0.01 [-0.07 to 0.04] mm), corneal power (-0.02 D [-0.15 to 0.19 d]), white-to-white distance (-0.13 [-0.43 to 0.17] mm), and pupil diameter (-0.27 [-0.79 to 1.33] mm). The limits of agreement, coefficient of variations, and intraclass correlation coefficients for MYAH-measured parameters were -0.04 to 0.04, 0.06%, and >0.99 for axial length; -0.24 to 0.19, 0.18%, and >0.99 for corneal power; -1.05 to 1.15, 0.57%, and 0.96 for white-to-white distance; and -0.17 to 0.21, 7.0%, and 0.76 for pupil diameter, with no significant difference between visits (p>0.05 for all), indicating good intersession repeatability. Similar intersession repeatability was also noted for Lenstar.

CONCLUSIONS

Findings show good intersession repeatability of the MYAH and good agreement with the Lenstar for axial length, corneal power, and white-to-white distance in young adults. Pupil diameter was more variable, likely due to the dynamic nature of the pupil. This study provides validation and supports the use of the MYAH for ocular biometry.

摘要

意义

在将新的生物测量仪器用于临床和研究应用之前，验证其与金标准的一致性并建立可重复性非常重要。

目的

本研究旨在调查 MYAH 光学生物测量仪和角膜地形图在健康年轻成年人中的日内可重复性，并检查其与 Lenstar LS900 光学生物测量仪的一致性。

方法

40 名参与者（平均年龄 25.2±3.1 岁）在 2 至 4 天内进行了两次就诊。每次就诊时，使用 MYAH 和 Lenstar LS 900 收集右眼的测量值，包括眼轴长度、角膜屈光力、白到白距离和瞳孔直径。使用 Bland-Altman 分析评估 MYAH 和 Lenstar 之间每个参数的日内一致性以及两种设备的日间可重复性。对于每种设备，计算变异系数和组内相关系数，并进行两次就诊之间的配对 t 检验，以评估日间可重复性。

结果

MYAH 和 Lenstar 之间发现了良好的一致性（平均差异[95% 一致性界限]），眼轴长度为-0.01[-0.07 至 0.04]mm），角膜屈光力为-0.02D[-0.15 至 0.19 d]），白到白距离为-0.13[-0.43 至 0.17]mm）和瞳孔直径为-0.27[-0.79 至 1.33]mm）。MYAH 测量参数的一致性界限、变异系数和组内相关系数分别为-0.04 至 0.04、0.06%和>0.99 用于眼轴长度；-0.24 至 0.19、0.18%和>0.99 用于角膜屈光力；-1.05 至 1.15、0.57%和 0.96 用于白到白距离；-0.17 至 0.21、7.0%和 0.76 用于瞳孔直径，两次就诊之间无显著差异（p>0.05 所有），表明日间可重复性良好。Lenstar 也观察到类似的日间可重复性。